Abstract BACKGROUND Mitochondrial DNA (mtDNA) encodes key proteins associated with
the process of oxidative phosphorylation. Defects to mtDNA cause severe disease …

Mitochondria are highly dynamic organelles and their distribution, structure and activity
affect a wide range of cellular functions. Mitochondrial membrane potential (∆ Ψm) is an …

Oocytes from aging ovaries contain mitochondria with morphological and genetic flaws. How
these flaws relate to phenotypes of oocyte developmental compromise associated with …

Stress can affect reproductive performance of lactating cows by targeting the ovarian pool of
follicles and their enclosed oocytes. Among the documented stressors are heat stress (ie …

STUDY QUESTION What part do mitochondria play in cases of diminished ovarian reserve
(DOR)? SUMMARY ANSWER Mitochondrial biogenesis in cumulus cells may be linked with …

Oocyte mitochondrial dysfunction has been proposed as a cause of high levels of
developmental retardation and arrest that occur in human preimplantation embryos …

Objective To investigate the clinical relevance of mitochondrial DNA (mtDNA) content as a
viability score in human euploid embryos. Design Retrospective analysis of mtDNA content …

Mitochondria play a central and multifaceted role in the mammalian egg and early embryo,
contributing to many different aspects of early development. While the contribution of …

Object To explore the mechanisms of ovarian aging, we performed overall analysis on the
age-related alterations of gene expression profiles in mouse germinal vesicle (GV) stage …

During mammalian oocyte maturation there are marked changes in the distribution of
mitochondria that supply the majority of the cellular ATP. Such redistribution of mitochondria …