Although the role of oxidative stress in maternal aging and infertility has been suggested, the
underlying mechanisms are not fully understood. The present study is designed to …

BACKGROUND Mitochondria are multitasking organelles involved in ATP synthesis,
reactive oxygen species (ROS) production, calcium signalling and apoptosis; and …

Environmental stress-induced alterations in oocyte mitochondria are suggested to
deleteriously affect developmental competence of the ovarian pool of oocytes. We examined …

Mitochondria, fundamental organelles in cell metabolism, and ATP synthesis are
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …

Mitochondria are the most prominent organelle in the oocyte. Somatic cells maintain a
healthy population of mitochondria by degrading damaged mitochondria via mitophagy, a …

Studies of human oocytes obtained from women of advanced reproductive age revealed that
spindles are frequently aberrant, with chromosomes sometimes failing to align properly at …

The consensus that assisted reproduction technologies (ART), like in vitro fertilization, to
induce oxidative stress (ie, the known) belies how oocyte/zygote mitochondria—a major …