Airway hyperresponsiveness is the excessive narrowing of the airway lumen caused by
stimuli that would cause little or no narrowing in the normal individual. It is one of the …

The etiology of airway hyperresponsiveness associated with asthma requires an
understanding of the regulatory mechanisms mediating human airway smooth muscle cell …

Publisher Summary Asthma and chronic obstructive pulmonary disease (COPD) are highly
complex airway-obstruction disease conditions. Chronic inflammation of airways is …

The chronic inflammatory response within the airways of asthmatics is associated with
structural changes termed airway remodeling. This remodeling process is a key feature of …

There is growing evidence indicating the existence of a causal relationship between
abnormal airway smooth muscle (ASM) function and airway hyper-responsiveness, a poorly …

Known to have affected around 340 million people across the world in 2018, asthma is a
prevalent chronic inflammatory disease of the airways. The symptoms such as wheezing …

Asthma as well as bronchiolitis obliterans and chronic bronchitis are chronic lung diseases
characterized by airflow obstruction and airway inflammation. Although asthma typically …

Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and
airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to …

Abstract lntracellular calcium ion is the key secondary messenger system of the cellular
processes in airway smooth muscle cells (ASMc). The treatment and regulation of Ca2+ in …

What airway smooth muscle definitely does in asthma is contract. Because it encircles the
airway, smooth muscle contraction narrows the airway lumen, thereby obstructing airflow …