The expression of recombinant Plasmodium falciparum sexual-stage proteins and assessment of naturally acquired transmission-blocking immunity

CK Kirima - 2019 - erepository.uonbi.ac.ke
Persons residing in regions endemic to malaria have been shown to develop antibodies
against gametocytes, which could subsequently prevent the progression of the parasite …

[HTML][HTML] Characterization of Naturally Acquired Immunity to a Panel of Antigens Expressed in Mature P. falciparum Gametocytes

MK Muthui, E Takashima, BR Omondi… - Frontiers in cellular …, 2021 - frontiersin.org
Introduction Naturally acquired immune responses against antigens expressed on the
surface of mature gametocytes develop in individuals living in malaria-endemic areas …

Plasmodium falciparum gametocyte-specific antibody profiling reveals boosting through natural infection and identifies potential markers of gametocyte exposure

J Skinner, CY Huang, M Waisberg… - Infection and …, 2015 - Am Soc Microbiol
Malaria elimination efforts would benefit from vaccines that block transmission of
Plasmodium falciparum gametocytes from humans to mosquitoes. A clear understanding of …

A longitudinal study of immune responses to Plasmodium falciparum sexual stage antigens in Tanzanian adults

JT Bousema, CJ Drakeley, J Kihonda… - Parasite …, 2007 - Wiley Online Library
Next to children, adults form a substantial part of the infectious reservoir that is responsible
for the spread of malaria. In this longitudinal study, we determined sexual stage immune …

Immunity to the sexual stages of Plasmodium falciparum in mothers, neonates and infants subject to intense and perennial malarial transmission

NIJ Akim, H Urassa, CJ Drakeley… - Annals of Tropical …, 2002 - Taylor & Francis
The bloodmeal of a mosquito that has fed Multiparous mothers and their newborn infants
were enrolled at the Saint Francis on an individual with a malarial infection may contain the …

Sexual-stage antibody responses to P. falciparum in endemic populations

JT Bousema, CJ Drakeley… - Current molecular …, 2006 - ingentaconnect.com
Gametocytes and sporogonic stages are responsible for the spread of disease and drug
resistance in the population. Sexual stage immunity affects the infectiousness of …

Naturally acquired immunity to sexual stage P. falciparum parasites

WJR Stone, KW Dantzler, SK Nilsson, CJ Drakeley… - Parasitology, 2016 - cambridge.org
Gametocytes are the specialized form of Plasmodium parasites that are responsible for
human-to-mosquito transmission of malaria. Transmission of gametocytes is highly effective …

[HTML][HTML] The acquisition of humoral immune responses targeting Plasmodium falciparum sexual stages in controlled human malaria infections

RM de Jong, M Alkema, T Oulton, E Dumont… - Frontiers in …, 2022 - frontiersin.org
Individuals infected with P. falciparum develop antibody responses to intra-erythrocytic
gametocyte proteins and exported gametocyte proteins present on the surface of infected …

[HTML][HTML] The Dynamics of Naturally Acquired Immune Responses to Plasmodium falciparum Sexual Stage Antigens Pfs230 & Pfs48/45 in a Low Endemic Area in …

T Bousema, W Roeffen, H Meijerink, H Mwerinde… - PloS one, 2010 - journals.plos.org
Background Naturally acquired immune responses against sexual stages of P. falciparum
can reduce the transmission of malaria from humans to mosquitoes. These antigens are …

[HTML][HTML] Immune Responses to the Sexual Stages of Plasmodium falciparum Parasites

JA Kengne-Ouafo, CJ Sutherland, FN Binka… - Frontiers in …, 2019 - frontiersin.org
Malaria infections remain a serious global health problem in the world, particularly among
children and pregnant women in Sub-Saharan Africa. Moreover, malaria control and …