Targeting vascular (endothelial) dysfunction
A Daiber, S Steven, A Weber… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …
years, with hypertension a significant risk factor for all causes of death. The endothelium that …
Oxidative stress and endothelial dysfunction
C Urso, G Caimi - Minerva medica, 2011 - europepmc.org
Endothelial dysfunction and oxidative stress are the main pathophysiological mechanisms of
several diseases such as hypertension, atherosclerosis, dyslipidemia, diabetes mellitus …
several diseases such as hypertension, atherosclerosis, dyslipidemia, diabetes mellitus …
[HTML][HTML] Targeting oxidative stress in disease: Promise and limitations of antioxidant therapy
HJ Forman, H Zhang - Nature Reviews Drug Discovery, 2021 - nature.com
Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …
Hyperglycemia-induced oxidative stress and its role in diabetes mellitus related cardiovascular diseases
T Vanessa Fiorentino, A Prioletta… - Current …, 2013 - ingentaconnect.com
Diabetes mellitus is associated to an increased risk of cardiovascular diseases.
Hyperglycemia is an important factor in cardiovascular damage, working through different …
Hyperglycemia is an important factor in cardiovascular damage, working through different …
Redox signaling in cardiovascular health and disease
NR Madamanchi, MS Runge - Free Radical Biology and Medicine, 2013 - Elsevier
Spatiotemporal regulation of the activity of a vast array of intracellular proteins and signaling
pathways by reactive oxygen species (ROS) governs normal cardiovascular function …
pathways by reactive oxygen species (ROS) governs normal cardiovascular function …
[HTML][HTML] The antioxidant therapy: new insights in the treatment of hypertension
D Sorriento, N De Luca, B Trimarco… - Frontiers in …, 2018 - frontiersin.org
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a key role in the
regulation of the physiological and pathological signaling within the vasculature. In …
regulation of the physiological and pathological signaling within the vasculature. In …
Oxidative stress–chronic kidney disease–cardiovascular disease: A vicious circle
Chronic kidney disease patient's progression to end-stage renal disease as well as their
high mortality are linked to cardiovascular disease. However, the high incidence rate of …
high mortality are linked to cardiovascular disease. However, the high incidence rate of …
Evolving concepts of oxidative stress and reactive oxygen species in cardiovascular disease
K Chen, JF Keaney - Current atherosclerosis reports, 2012 - Springer
Cardiovascular disease (CVD) continues to be a substantial health-care burden, despite
recent treatment advances. Oxidative stress has long been regarded as a key …
recent treatment advances. Oxidative stress has long been regarded as a key …
[HTML][HTML] Role of oxidative stress in the pathogenesis of atherothrombotic diseases
Oxidative stress is generated by the imbalance between reactive oxygen species (ROS)
formation and antioxidant scavenger system's activity. Increased ROS, such as superoxide …
formation and antioxidant scavenger system's activity. Increased ROS, such as superoxide …
Management of oxidative stress and inflammation in cardiovascular diseases: mechanisms and challenges
Cardiovascular diseases (CVDs) have diverse physiopathological mechanisms with
interconnected oxidative stress and inflammation as one of the common etiologies which …
interconnected oxidative stress and inflammation as one of the common etiologies which …