The choroid plexus (CP) tissue forms the blood-cerebrospinal fluid barrier (BCSFB)-a
unique interface which plays a critical role in effective homeostasis of the central nervous …

The blood–cerebrospinal fluid barrier (BCSFB) is a highly dynamic transport interface that
serves brain homeostasis. To date, however, understanding of its role in brain development …

Abstract VERHEGGEN, ICM, W. Freeze, J. de Jong, J. Jansen, A. Postma, M. van Boxtel, F.
Verhey and W. Backes. The application of contrast-enhanced MRI in the assessment of …

Chronic hypertension is a major risk factor for the development of neurodegenerative
disease, yet the etiology of hypertension-driven neurodegeneration remains poorly …

Background: We have recently developed a MRI technique that quantifies the rate of arterial
blood water delivery to ventricular CSF, a non-invasive surrogate measure of Blood …

Pharmacological MRI (phMRI) studies seek to capture changes in brain haemodynamics in
response to a drug. This provides a methodological platform for the evaluation of novel …

The glymphatics system describes a CSF-mediated clearance pathway for the removal of
potentially harmful molecules, such as amyloid beta, from the brain. As such, its components …

INTRODUCTION Choroid plexus (CP) dysfunction is thought to contribute to toxic protein
build-up in neurodegenerative disorders, including Alzheimer's disease (AD). However, the …

Purpose Clearance of cerebrospinal fluid (CSF) is important for the removal of toxins from
the brain, with implications for neurodegenerative diseases. Imaging evaluation of CSF …

Cerebrospinal fluid (CSF) has historically been considered to function as a sink for brain‐
derived waste disposal. Recent work suggested that CSF interacts even more intensely with …