Comparing the effects of low-dose ketamine, fentanyl, and morphine on hemorrhagic tolerance and analgesia in humans
Hemorrhage is a leading cause of preventable battlefield and civilian trauma deaths.
Ketamine, fentanyl, and morphine are recommended analgesics for use in the prehospital …
Ketamine, fentanyl, and morphine are recommended analgesics for use in the prehospital …
Low‐dose ketamine affects blood pressure, but not muscle sympathetic nerve activity, during progressive central hypovolemia without altering tolerance
Key points Haemorrhage is the leading cause of battlefield and civilian trauma deaths.
Given that a haemorrhagic injury on the battlefield is almost always associated with pain, it is …
Given that a haemorrhagic injury on the battlefield is almost always associated with pain, it is …
Low-dose fentanyl does not alter muscle sympathetic nerve activity, blood pressure, or tolerance during progressive central hypovolemia
Hemorrhage is a leading cause of battlefield and civilian trauma deaths. Several pain
medications, including fentanyl, are recommended for use in the prehospital (ie, field setting) …
medications, including fentanyl, are recommended for use in the prehospital (ie, field setting) …
Low-dose morphine reduces tolerance to central hypovolemia in healthy adults without affecting muscle sympathetic outflow
Hemorrhage is a leading cause of preventable battlefield and civilian trauma deaths. Low-
dose (ie, an analgesic dose) morphine is recommended for use in the prehospital (ie, field) …
dose (ie, an analgesic dose) morphine is recommended for use in the prehospital (ie, field) …
Intravenous low-dose ketamine provides greater pain control compared to fentanyl in a civilian prehospital trauma system: a propensity matched analysis
ES Bronsky, C Koola, A Orlando… - Prehospital …, 2019 - Taylor & Francis
Objective: A few studies report comparable analgesic efficacy between low-dose ketamine
and opioids such as morphine or fentanyl; however, limited research has explored the safety …
and opioids such as morphine or fentanyl; however, limited research has explored the safety …
[HTML][HTML] Integrative Cardiovascular Physiology and Pathophysiology: Low-dose morphine reduces tolerance to central hypovolemia in healthy adults without affecting …
Hemorrhage is a leading cause of preventable battlefield and civilian trauma deaths. Low-
dose (ie, an analgesic dose) morphine is recommended for use in the prehospital (ie, field) …
dose (ie, an analgesic dose) morphine is recommended for use in the prehospital (ie, field) …
Fentanyl impairs but ketamine preserves the microcirculatory response to hemorrhage
L Xiang, AS Calderon, HG Klemcke… - Journal of Trauma …, 2020 - journals.lww.com
BACKGROUND Peripheral vasoconstriction is the most critical compensating mechanism
following hemorrhage to maintain blood pressure. On the battlefield, ketamine rather than …
following hemorrhage to maintain blood pressure. On the battlefield, ketamine rather than …
Effects of opioid analgesics (morphine, fentanyl, and sufentanil) and trauma on survival time after severe conscious hemorrhage in rats
HG Klemcke, ML Calderon, CM Rodriguez… - The FASEB …, 2019 - Wiley Online Library
Background Currently, opioid analgesics are not recommended for use on the battlefield for
Soldiers with severe hemorrhage, although they are still used during such situations …
Soldiers with severe hemorrhage, although they are still used during such situations …
Comparison of the effects of ketamine and morphine on performance of representative military tasks
SJ Gaydos, AM Kelley, CM Grandizio, JR Athy… - The Journal of …, 2015 - Elsevier
Background When providing care under combat or hostile conditions, it may be necessary
for a casualty to remain engaged in military tasks after being wounded. Prehospital care …
for a casualty to remain engaged in military tasks after being wounded. Prehospital care …
Opioid sparing effect of ketamine in military prehospital pain management—A retrospective study
B Cohen, T Talmy, S Gelikas… - Journal of Trauma …, 2022 - journals.lww.com
BACKGROUND Opioids are the most commonly used analgesics in acute trauma, but are
limited by slow onset and significant adverse effects. Ketamine is an effective and widely …
limited by slow onset and significant adverse effects. Ketamine is an effective and widely …