New treatments for chronic obstructive pulmonary disease and viable formulation/device options for inhalation therapy

S Onoue, S Misaka, Y Kawabata… - Expert Opinion on Drug …, 2009 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is an increasingly important cause of
morbidity and mortality, pathological features of which are pulmonary inflammation and …

[HTML][HTML] The future of inhalation therapy in chronic obstructive pulmonary disease

M Cazzola, J Ora, L Calzetta, P Rogliani… - Current Research in …, 2022 - Elsevier
The inhaled route is critical for the administration of drugs to treat patients suffering from
COPD, but there is still an unmet need for new and innovative inhalers to address some …

Advances in the management of chronic obstructive pulmonary disease

TM Ziedalski, V Sankaranarayanan… - Expert Opinion on …, 2003 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a progressive and irreversible airflow
limitation with extreme economic and social burden. It is estimated that over the next two …

Inhaled treatment for chronic obstructive pulmonary disease: what's new and how does it fit?

GP Currie, BJ Lipworth - QJM: An International Journal of …, 2016 - academic.oup.com
Since chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
obstruction, inhaled bronchodilators form the mainstay of treatment. A variety of new inhaled …

Dry powder inhalers in COPD, lung inflammation and pulmonary infections

P Muralidharan, D Hayes Jr… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: The number of pulmonary diseases that are effectively treated by aerosolized
medicine continues to grow. Areas covered: These diseases include chronic obstructive …

Inhaled therapies for asthma and chronic obstructive pulmonary disease

Y Liang, JCW Mak - Current Pharmaceutical Design, 2021 - ingentaconnect.com
Asthma and chronic obstructive pulmonary disease (COPD) are obstructive lung diseases
which are characterized by chronic inflammation and an increase in mucus production, and …

Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease

M Cazzola, F Cavalli, OS Usmani… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Proper device selection is crucial for the clinical results of inhalation therapy.
However, none of the available devices fully conforms to the requirements for delivering …

Nebulized therapies in COPD: past, present, and the future

IZ Barjaktarevic, AP Milstone - International journal of chronic …, 2020 - Taylor & Francis
Current guidelines recommend inhalation therapy as the preferred route of drug
administration for treating patients with chronic obstructive pulmonary disease (COPD) …

New therapies for chronic obstructive pulmonary disease

G Krishna, V Sankaranarayanan… - Expert opinion on …, 2004 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is the most common lung disease, carrying
a significant mortality and morbidity. None of the therapeutic interventions currently available …

Dry powder inhalers for optimal drug delivery

SP Newman - Expert opinion on biological therapy, 2004 - Taylor & Francis
Dry powder inhalers (DPIs) have been available for delivering drugs to the lungs for over 30
years. In the last decade there has been a big increase in DPI development, resulting partly …