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The brain–blood barrier (BBB) tightly limits immune cell migration into the central nervous
system (CNS), avoiding unwanted inflammation under the normal state. However, immune …

Parallel advances in neuroscience and immunology established the anatomical and cellular
basis for bidirectional interactions between the nervous and immune systems. Like other …

The central nervous system regulates the innate immune system by elaborating anti‐
inflammatory hormone cascades in response to bacterial products and immune mediators …

That the mind can influence the body during health and disease is an ancient notion which,
in part because of its origins in anecdotal observations, has been an often and sometimes …

The neural regulation of organs can be categorized as systemic or local. Whereas systemic
regulation by the hypothalamus–pituitary–adrenal gland-mediated release of steroid …

Inflammation can cause damage and even death. What controls this primitive and potentially
lethal innate immune response to injury and infection? Molecular and neurophysiological …

The immune and nervous systems share many features, including receptor and ligand
expression, enabling efficient communication between the two. Accumulating evidence …

Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …

The immune system and the central nervous system form a bi-directional communication
network. The critical roles of pro-inflammatory cytokines in both the periphery and the …