One of the first-line drugs for empirical antibiotic therapy in patients with hospital-acquired
infections is meropenem. An often neglected problem in sepsis is that patients with a normal …

Background Meropenem is an anti-Gram-negative antimicrobial, the time-dependent activity
of which may be maximized through administration by continuous infusion. Objectives The …

Meropenem is frequently prescribed in critically ill children receiving continuous renal
replacement therapy (CRRT). We previously used clinical trial simulations to evaluate …

Objective: Chronic kidney disease (CKD) has significant effects on renal clearance of drugs.
The application of antibiotics in CKD patients to achieve the desired therapeutic effect is …

Objective Meropenem is a broad‐spectrum antibiotic used for severe infections. In patients
with chronic end‐stage renal failure, meropenem clearance is reduced and doses must be …

Pharmacokinetics and dosing regimen of meropenem in critical... : Critical Care Medicine
Pharmacokinetics and dosing regimen of meropenem in critically ill patients receiving …

Objective: To systematically review evidence comparing traditional and alternative dosing
strategies for meropenem, based on clinical and pharmacoeconomic outcomes. Data …

The objective of this study was to describe the pharmacokinetics of meropenem,
administered by continuous infusion (CI) or intermittent bolus (IB), in critically ill patients …

Background Pharmacists have been involved in promoting the proper and safe use of
antimicrobial drugs in our institution since 2010. Setting Kochi Medical School Hospital …

What is known and Objective Meropenem, a broad‐spectrum carbapenem, is frequently
used to treat severe bacterial infections in critically ill children. Recommendations for …