Outer membrane protein A inhibits the degradation of caspase-1 to regulate NLRP3 inflammasome activation and exacerbate the Acinetobacter baumannii pulmonary …
Y Li, C Peng, D Zhao, L Liu, B Guo, M Shi, Y Xiao… - Microbial …, 2021 - Elsevier
Abstract Acinetobacter baumannii (A. baumannii), one of the major pathogens that causes
severe nosocomial infections, is characterised by a high prevalence of drug resistance. It …
severe nosocomial infections, is characterised by a high prevalence of drug resistance. It …
[HTML][HTML] NLRP3 inflammasome pathway has a critical role in the host immunity against clinically relevant Acinetobacter baumannii pulmonary infection
N Dikshit, SD Kale, HJ Khameneh, V Balamuralidhar… - Mucosal …, 2018 - Elsevier
The opportunistic Gram-negative bacterium Acinetobacter baumannii (AB) is a leading
cause of life-threatening nosocomial pneumonia. Outbreaks of multidrug resistant (MDR)-AB …
cause of life-threatening nosocomial pneumonia. Outbreaks of multidrug resistant (MDR)-AB …
[HTML][HTML] Acinetobacter baumannii outer membrane protein 34 elicits NLRP3 inflammasome activation via mitochondria-derived reactive oxygen species in RAW264. 7 …
Z An, J Su - Microbes and Infection, 2019 - Elsevier
Acinetobacter baumannii (A. baumannii) is a Gram-negative bacterium, which acts as an
opportunistic pathogen and causes hospital-acquired pneumonia and bacteremia by …
opportunistic pathogen and causes hospital-acquired pneumonia and bacteremia by …
Differential activation of NLRP3 inflammasome by Acinetobacter baumannii strains
Acinetobacter baumannii is an emerging nosocomial, opportunistic pathogen with growing
clinical significance globally. A. baumannii has an exceptional ability to rapidly develop drug …
clinical significance globally. A. baumannii has an exceptional ability to rapidly develop drug …
NLRP3 inflammasome mediates interleukin‐1β production in immune cells in response to Acinetobacter baumannii and contributes to pulmonary inflammation in …
MJ Kang, SG Jo, DJ Kim, JH Park - Immunology, 2017 - Wiley Online Library
Acinetobacter baumannii is a multi‐drug resistant, Gram‐negative bacteria and infection
with this organism is one of the major causes of mortality in intensive care units …
with this organism is one of the major causes of mortality in intensive care units …
Aeromonas sobria Induces Proinflammatory Cytokines Production in Mouse Macrophages via Activating NLRP3 Inflammasome Signaling Pathways
W Zhang, Z Li, H Yang, G Wang, G Liu… - Frontiers in Cellular …, 2021 - frontiersin.org
Aeromonas sobria, a common conditional pathogenic bacteria, is widely distributed in the
environment and causes gastroenteritis in humans or septicemia in fish. Of all Aeromonas …
environment and causes gastroenteritis in humans or septicemia in fish. Of all Aeromonas …
Pseudomonas aeruginosa triggers macrophage autophagy to escape intracellular killing by activation of the NLRP3 inflammasome
Q Deng, Y Wang, Y Zhang, M Li, D Li… - Infection and …, 2016 - Am Soc Microbiol
Assembly of the inflammasome has recently been identified to be a critical event in the
initiation of inflammation. However, its role in bacterial killing remains unclear. Our study …
initiation of inflammation. However, its role in bacterial killing remains unclear. Our study …
Acinetobacter baumannii Outer Membrane Protein A Induces Pulmonary Epithelial Barrier Dysfunction and Bacterial Translocation Through The TLR2/IQGAP1 Axis
W Zhang, H Zhou, Y Jiang, J He, Y Yao… - Frontiers in …, 2022 - frontiersin.org
Pulmonary epithelial barrier dysfunction is a critical pathophysiological process in
pneumonia and associated invasive infections, such as those caused by Acinetobacter …
pneumonia and associated invasive infections, such as those caused by Acinetobacter …
P. aeruginosa biofilm activates the NLRP3 inflammasomes in vitro
Q Tan, Q Ai, Y He, F Li, J Yu - Microbial Pathogenesis, 2022 - Elsevier
The ability of P. aeruginosa to form biofilms renders common treatments inefficient, thereby
promoting chronic infection. Inflammasomes activate caspase-1, which is important for the …
promoting chronic infection. Inflammasomes activate caspase-1, which is important for the …
[HTML][HTML] Necroptosis signaling and NLRP3 inflammasome cross-talking in epithelium facilitate Pseudomonas aeruginosa mediated lung injury
H Li, J Guan, J Chen, W Sun, H Chen, Y Wen… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Pseudomonas aeruginosa induced acute lung injury is such a serious risk to public health,
but the pathological regulation remains unclear. Here, we reported that PA mediated …
but the pathological regulation remains unclear. Here, we reported that PA mediated …
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