In vivo immunoprotective comparison between recombinant protein and DNA vaccine of Eimeria tenella surface antigen 4

P Zhao, Y Li, Y Zhou, J Zhao, R Fang - Veterinary parasitology, 2020 - Elsevier
Eimeria tenella, belonging to protozoon, is the causative agent of cecal coccidiosis in
chicken and causes enormous impacts for poultry industry. The surface antigens of …

Evaluation of immunoprotective effects of recombinant proteins and DNA vaccines derived from Eimeria tenella surface antigen 6 and 15 in vivo

T Geng, L Luo, Y Wang, B Shen, R Fang, M Hu… - Parasitology …, 2022 - Springer
Coccidiosis is an intestinal parasitic disease that causes huge economic losses to the
poultry industry globally. Eimeria tenella belonging to protozoon is the causative agent of …

Evaluation of immunoprotective effects of recombinant protein and DNA vaccine based on Eimeria tenella surface antigen 16 and 22 in vivo

P Zhao, C Wang, J Ding, C Zhao, Y Xia, Y Hu… - Parasitology …, 2021 - Springer
Coccidiosis triggered by Eimeria tenella is accompanied by haemorrhagic caecum and high
morbidity. Vaccines are preferable choices to replace chemical drugs against coccidiosis …

Partial protective of chickens against Eimeria tenella challenge with recombinant EtMIC-1 antigen

NS Qi, YY Wang, SQ Liao, CY Wu, MN Lv, J Li… - Parasitology …, 2013 - Springer
Eimeria tenella microneme protein 1 (EtMIC-1) is highly conserved with TgMIC-2, which is
involved in parasite binding specifically to host cells. Little is known about the immune …

Passive immunization with Eimeria tenella gametocyte antigen 56 (EtGAM56) specific antibodies and active immunization trial with the epitope containing peptide

S Wiedmer, AA Alnassan, B Volke, A Thabet… - Veterinary …, 2017 - Elsevier
Eimeria species cause avian coccidiosis leading to substantial economic losses in the
poultry industry. Hence, anticoccidial drugs and vaccines have been used to combat this …

Improving the immunogenicity and protective efficacy of the EtMIC2 protein against Eimeria tenella infection through random mutagenesis

Z Chen, X Wang, N Zhao, L Han, F Wang, H Li, Y Cui… - Vaccine, 2018 - Elsevier
In recent years, directed evolution has emerged as an efficient tool to develop and identify
novel protein variants. Eimeria tenella microneme-2 (EtMIC2) is a promising vaccine …

[HTML][HTML] Evaluation of 4 merozoite antigens as candidate vaccines against Eimeria tenella infection

X Song, X Yang, T Zhang, J Liu, Q Liu - Poultry Science, 2021 - Elsevier
Coccidiosis, caused by parasites of the genus Eimeria, is one of the most widespread and
economically detrimental diseases in the global poultry industry. Because the merozoite …

Pichia pastoris expressed EtMic2 protein as a potential vaccine against chicken coccidiosis

J Zhang, P Chen, H Sun, Q Liu, L Wang, T Wang… - Veterinary …, 2014 - Elsevier
Chicken coccidiosis caused by Eimeria species leads to tremendous economic losses to the
avian industry worldwide. Identification of parasite life cycle specific antigens is a critical step …

Development of transgenic lines of Eimeria tenella expressing M2e-enhanced yellow fluorescent protein (M2e-EYFP)

X Liu, J Zou, G Yin, H Su, X Huang, J Li, L Xie… - Veterinary …, 2013 - Elsevier
Eimeria parasites are obligate intracellular apicomplexan protists that can cause coccidiosis,
resulting in substantial economic losses in the poultry industry annually. As the component …

A potential vaccine candidate towards chicken coccidiosis mediated by recombinant Lactobacillus plantarum with surface displayed EtMIC2 protein

HB Huang, YL Jiang, FY Zhou, CW Shi, WT Yang… - Experimental …, 2020 - Elsevier
Eimeria tenella (E. tenella) has caused severe economic loss in chicken production,
especially after the forbidden use of antibiotics in feed. Considering the drug resistant …