Chlorogenic acid/chromium supplement rescues diet-induced insulin resistance and obesity in mice

HE Ghadieh, ZN Smiley, MW Kopfman, MG Najjar… - Nutrition & …, 2015 - Springer
Abdominal obesity is a major risk factor for insulin resistance, type 2 diabetes and
cardiovascular diseases. Dietary fat induces insulin resistance in humans and rodents. The …

Chromium malate alleviates high-glucose and insulin resistance in L6 skeletal muscle cells by regulating glucose uptake and insulin sensitivity signaling pathways

W Feng, Y Ding, W Zhang, Y Chen, Q Li, W Wang… - Biometals, 2018 - Springer
Previous study revealed that chromium malate improved the regulation of fasting blood
glucose and insulin resistance in type 2 diabetic rats. In this study, the effect of chromium …

The effects of chromium picolinate on glucose and lipid metabolism in running rats

R Pala, MA Sari, F Erten, B Er, M Tuzcu, C Orhan… - Journal of Trace …, 2020 - Elsevier
Abstract Background Chromium picolinate (CrPic) is commonly used to reduce muscle
fatigue after exercise. We aimed to elucidate the effects of CrPic on glucose and lipid …

Chromium is not an essential trace element for mammals: effects of a “low-chromium” diet

KR Di Bona, S Love, NR Rhodes, D McAdory… - JBIC Journal of …, 2011 - Springer
Chromium was proposed to be an essential trace element over 50 years ago and has been
accepted as an essential element for over 30 years. However, the studies on which …

Effect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated rat

K Sahin, M Onderci, M Tuzcu, B Ustundag, G Cikim… - Metabolism, 2007 - Elsevier
Chromium supplements are widely used as an alternative remedy for type 2 diabetes
mellitus (T2DM). In vitro study findings show that chromium picolinate (CrPic) may improve …

Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic …

GR Pattar, L Tackett, P Liu, JS Elmendorf - Mutation Research/Genetic …, 2006 - Elsevier
Since trivalent chromium (Cr3+) enhances glucose metabolism, interest in the use of Cr3+
as a therapy for type 2 diabetes has grown in the mainstream medical community. Moreover …

Isoproterenol exacerbates hyperglycemia and modulates chromium distribution in mice fed with a high fat diet

GR Chang, WK Chen, PH Hou, FC Mao - Journal of Trace Elements in …, 2017 - Elsevier
Background and purpose Isoproterenol (ISO), a nonselective β-adrenoceptor agonist for
treating bradycardia and asthma, has been proposed to raise blood glucose level. Little is …

Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice

N Sreejayan, F Dong, MR Kandadi, X Yang, J Ren - Obesity, 2008 - Wiley Online Library
Objective: Chromium has gained popularity as a nutritional supplement for diabetic patients.
This study evaluated the effect of chronic administration of a chromium complex of d …

Inverse association of plasma chromium levels with newly diagnosed type 2 diabetes: A case-control study

S Chen, X Jin, Z Shan, S Li, J Yin, T Sun, C Luo… - Nutrients, 2017 - mdpi.com
Chromium has long been known as an enhancer of insulin action. However, the role of
chromium in the development of type 2 diabetes mellitus (T2DM) in humans remains …

Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus

WT Cefalu, J Rood, P Pinsonat, J Qin, O Sereda… - Metabolism, 2010 - Elsevier
The objective of the study was to provide a comprehensive evaluation of chromium (Cr)
supplementation on metabolic parameters in a cohort of type 2 diabetes mellitus subjects …