Lipid altering-efficacy of ezetimibe co-administered with simvastatin compared with rosuvastatin: a meta-analysis of pooled data from 14 clinical trials

A Catapano, WE Brady, TR King… - … medical research and …, 2005 - Taylor & Francis
Objective: Results of direct comparative studies between ezetimibe/simvastatin and
rosuvastatin therapies have not been reported. Both of these treatment options offer …

Efficacy and safety of ezetimibe and rosuvastatin combination therapy versus those of rosuvastatin monotherapy in patients with primary hypercholesterolemia

W Kim, YE Yoon, SH Shin, JW Bae, BK Hong… - Clinical Therapeutics, 2018 - Elsevier
Purpose The aim of this study was to evaluate the safety and efficacy of combination
treatment of rosuvastatin with ezetimibe in patients with primary hypercholesterolemia …

Combination therapy of ezetimibe and rosuvastatin for dyslipidemia: current insights

MR Chilbert, D VanDuyn, S Salah… - Drug design …, 2022 - Taylor & Francis
Cardiovascular disease is one of the leading causes of death around the world with various
efforts being made to reduce risk in patients through preventive measures. One major …

Safety and efficacy of ezetimibe added on to rosuvastatin 5 or 10 mg versus up-titration of rosuvastatin in patients with hypercholesterolemia (the ACTE Study)

HE Bays, MH Davidson, R Massaad, D Flaim… - The American journal of …, 2011 - Elsevier
The present multicenter, 6-week, randomized, double-blind, parallel-group, clinical trial
evaluated the safety and efficacy of ezetimibe (10 mg) added to stable rosuvastatin therapy …

[HTML][HTML] A phase III, multicenter, randomized, double-blind, active comparator clinical trial to compare the efficacy and safety of combination therapy with ezetimibe and …

SJ Hong, HS Jeong, JC Ahn, DH Cha, KH Won… - Clinical …, 2018 - Elsevier
Purpose Combination therapy with ezetimibe and statins is recommended in cases of statin
intolerance or insufficiency. The objective of this study was to compare the efficacy and …

Lipid-lowering effects of ezetimibe and simvastatin in combination

N Ijioma, JG Robinson - Expert review of cardiovascular therapy, 2011 - Taylor & Francis
Ezetimibe/simvastatin is a combination of a statin and a cholesterol absorption inhibitor. This
article reviews current information on the pharmacology, clinical efficacy and safety of …

Ezetimibe and rosuvastatin combination treatment can reduce the dose of rosuvastatin without compromising its lipid-lowering efficacy

MY Rhee, KJ Kim, SH Kim, YW Yoon, SW Rha… - Clinical Therapeutics, 2019 - Elsevier
Purpose The goal of this study was to compare the lipid-lowering efficacy of the combination
of ezetimibe and low-or intermediate-intensity statin therapy versus that of high-intensity …

Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients

AL Catapano, MH Davidson… - … medical research and …, 2006 - Taylor & Francis
Objective: To assess the lipid-altering efficacy and safety of ezetimibe/simvastatin single
tablet product compared with rosuvastatin at the approved usual starting, next highest, and …

Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial

AC Goldberg, A Sapre, J Liu, R Capece… - Mayo Clinic …, 2004 - Elsevier
Objective To compare the efficacy and safety of 10 mg of ezetimibe coadministered with
simvastatin with the safety and efficacy of simvastatin monotherapy for patients with …

Ezetimibe plus simvastatin for the treatment of hypercholesterolemia

SE Gryn, RA Hegele - Expert opinion on pharmacotherapy, 2015 - Taylor & Francis
Introduction: Cardiovascular disease is a major cause of death, and hypercholesterolemia is
a major risk factor. Statins, with simvastatin among the most widely used, have ample …