Setting cutoff concentrations for immunoassay screening of postmortem blood

IB Collison, VR Spiehler… - Journal of forensic …, 1998 - asmedigitalcollection.asme.org
The objective of this study was to establish the optimum immunoassay cutoff concentrations
for screening postmortem blood from coroner's cases for drugs of abuse with a coated tube …

Validation of an automated microplate enzyme immunoassay for screening of postmortem blood for drugs of abuse

VR Spiehler, IB Collison, PR Sedgwick… - Journal of analytical …, 1998 - academic.oup.com
The objective of this study was to compare the sensitivity and specificity of an enzyme
immunoassay employing antibodies bound to a microtiter plate (MPEIA) with those of two …

Screening postmortem blood and tissues for nine cases of drugs of abuse using automated microplate immunoassay

KA Moore, C Werner, RM Zannelli, B Levine… - Forensic science …, 1999 - Elsevier
A commercially available enzyme-linked immunosorbant assay (ELISA) was evaluated as a
screening procedure for the detection of nine classes of abused drugs in postmortem blood …

Performance of immunoassays in screening for opiates, cannabinoids and amphetamines in post-mortem blood

Y Hino, I Ojanperä, I Rasanen, E Vuori - Forensic science international, 2003 - Elsevier
Several immunoassay methods for screening of abused drugs in whole blood were
evaluated in post-mortem forensic toxicology. Blood samples known to be positive or …

Radioimmunoassay screening and GC/MS confirmation of whole blood samples for drugs of abuse

VR Spiehler, P Sedgwick - Journal of analytical toxicology, 1985 - academic.oup.com
From 1981 to 1984, an average of 300 radioimmunoassay screens on whole blood were
performed each week in the authors' laboratory. Most samples were screened for opiates …

Optimization of cloned enzyme donor immunoassay cut-offs for drugs of abuse in post-mortem whole blood

G Pelletti, F Rossi, M Garagnani, R Barone… - Forensic science …, 2020 - Elsevier
Introduction Immunoassay (IA) tests are not widely applied in post-mortem samples, since
they are based on technologies requiring relatively non-viscous specimens, and compounds …

Choice of an ELISA assay for screening postmortem blood for amphetamine and/or methamphetamine

T Kupiec, L DeCicco, V Spiehler… - Journal of analytical …, 2002 - academic.oup.com
The object of this study was to evaluate the suitability of the Neogen Corp. microtiter plate
enzyme-linked immunoassays (ELISA) for the screening of postmortem blood for …

Requirements for bioanalytical procedures in postmortem toxicology

OH Drummer - Analytical and bioanalytical chemistry, 2007 - Springer
The application of analytical techniques in postmortem toxicology is often more difficult than
in other forms of forensic toxicology owing to the variable and often degraded nature of the …

Validation of a microtiter plate ELISA for screening of postmortem blood for opiates and benzodiazepines

P Kemp, G Sneed, T Kupiec… - Journal of analytical …, 2002 - academic.oup.com
The object of this study was to evaluate the suitability of the Neogen Corp. microtiter plate
enzyme-linked immunoassays (ELISA) for opiates and benzodiazepines for screening of …

Forensic immunochemistry

K Aoki, T Yoshida, Y Kuroiwa - Forensic science international, 1996 - Elsevier
Immunoassay has been established with polyclonal or monoclonal antibody even for a low
molecular weight compound which has no antigenicity. In spite of the cross-reactivities of an …