Long term exposure to tenofovir disoproxil fumarate-containing antiretroviral therapy is associated with renal impairment in an African cohort of HIV-infected adults
Objectives and Method: There are growing concerns of tenofovir disoproxil fumarate (TDF)–
associated renal toxicity. We evaluated the effect of long-term TDF exposure on renal …
associated renal toxicity. We evaluated the effect of long-term TDF exposure on renal …
A comparison of tenofovir-associated renal function changes in HIV-infected African Americans vs Caucasians
CK Lao, C Gruta, MDV John, J Cocohoba - Journal of the National Medical …, 2011 - Elsevier
Background The effects of tenofovir on renal function have been measured in multiple
studies. Although African Americans are at a higher risk of developing chronic kidney …
studies. Although African Americans are at a higher risk of developing chronic kidney …
[HTML][HTML] Incidence and predictors of tenofovir disoproxil fumarate-induced renal impairment in HIV infected Nigerian patients
Methods This retrospective cohort analysis included patients aged≥ 16 years that initiated
ART between January 2008 and December 2011. Renal impairment, defined as glomerular …
ART between January 2008 and December 2011. Renal impairment, defined as glomerular …
Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir …
M Ikeda, Y Wakabayashi, K Okamoto… - AIDS Research and …, 2021 - Springer
Background Antiretrovirals, including tenofovir, can suppress human immunodeficiency
virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are …
virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are …
Long-term exposure to tenofovir continuously decrease renal function in HIV-1-infected patients with low body weight: results from 10 years of follow-up
T Nishijima, Y Kawasaki, N Tanaka, D Mizushima… - Aids, 2014 - journals.lww.com
Objectives: To investigate the effect of long-term tenofovir disoproxil fumarate (TDF) use on
renal function, especially in patients with low body weight who are vulnerable to TDF …
renal function, especially in patients with low body weight who are vulnerable to TDF …
Prospective study to assess progression of renal markers after interruption of tenofovir due to nephrotoxicity
A Bonjoch, P Echeverría… - BioMed research …, 2016 - Wiley Online Library
Background. Prospective studies about the reversibility of tenofovir disoproxil fumarate‐(TDF‐
) related renal impairment remain scarce. Methods. This is an observational prospective …
) related renal impairment remain scarce. Methods. This is an observational prospective …
Tenofovir-associated kidney disease in Africans: a systematic review
TJ Mtisi, CE Ndhlovu, CC Maponga… - AIDS Research and …, 2019 - Springer
Background Data on chronic kidney disease development in HIV infection is important
towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa …
towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa …
[HTML][HTML] Tenofovir nephropathy in a patient with human immunodeficiency virus
WS Tsai, LS Wang, YH Hsu, YL Lin, TC Fang… - Tzu Chi Medical …, 2015 - Elsevier
Tenofovir is an effective and widely used antiretroviral drug for the treatment of both human
immunodeficiency virus (HIV) and hepatitis B virus infection. Although large clinical studies …
immunodeficiency virus (HIV) and hepatitis B virus infection. Although large clinical studies …
Renal safety of a tenofovir-containing first line regimen: experience from an antiretroviral cohort in rural Lesotho
H Bygrave, K Kranzer, K Hilderbrand, G Jouquet… - PloS one, 2011 - journals.plos.org
Introduction Current guidelines contraindicate TDF use when creatinine clearance (CrCl)
falls below 50 ml/min. We report prevalence of abnormal renal function at baseline and …
falls below 50 ml/min. We report prevalence of abnormal renal function at baseline and …
Tenofovir-associated kidney toxicity in HIV-infected patients: a review of the evidence
Tenofovir (TDF) is an effective and widely used treatment for both human immunodeficiency
virus (HIV) and hepatitis B virus infection. Although studies suggest that TDF has a low …
virus (HIV) and hepatitis B virus infection. Although studies suggest that TDF has a low …