Physiological considerations of functional magnetic resonance imaging in animal models

A Sumiyoshi, RJ Keeley, H Lu - Biological Psychiatry: Cognitive …, 2019 - Elsevier
Characterizing the nature and underlying neurobiological causes of psychiatric and
neurological diseases at the circuit and network levels has remained elusive and …

Technical and conceptual considerations for performing and interpreting functional MRI studies in awake rats

M Febo - Frontiers in psychiatry, 2011 - frontiersin.org
Functional neuroimaging studies in rodents have the potential to provide insight into
neurodevelopmental and psychiatric conditions. The strength of the technique lies in its non …

Functional magnetic resonance imaging in rodents: an unique tool to study in vivo pharmacologic neuromodulation

E Jonckers, A Van der Linden, M Verhoye - Current opinion in …, 2013 - Elsevier
Highlights•fMRI provides information on drug-induced modulation of activity of the
brain.•rsfMRI reveals drug-induced modulation of functional connectivity in brain …

A novel anesthesia regime enables neurofunctional studies and imaging genetics across mouse strains

MM Petrinovic, G Hankov, A Schroeter, A Bruns… - Scientific reports, 2016 - nature.com
Functional magnetic resonance imaging (fMRI) has revolutionized neuroscience by opening
a unique window that allows neurocircuitry function and pathological alterations to be …

Current status of functional MRI on small animals: application to physiology, pathophysiology, and cognition

A Van der Linden, N Van Camp… - NMR in Biomedicine …, 2007 - Wiley Online Library
This review aims to make the reader aware of the potential of functional MRI (fMRI) in brain
activation studies in small animal models. As small animals generally require anaesthesia …

The (un) conscious mouse as a model for human brain functions: key principles of anesthesia and their impact on translational neuroimaging

HM Reimann, T Niendorf - Frontiers in systems neuroscience, 2020 - frontiersin.org
In recent years, technical and procedural advances have brought functional magnetic
resonance imaging (fMRI) to the field of murine neuroscience. Due to its unique capacity to …

[HTML][HTML] Time to wake up: Studying neurovascular coupling and brain-wide circuit function in the un-anesthetized animal

YR Gao, Y Ma, Q Zhang, AT Winder, Z Liang, L Antinori… - Neuroimage, 2017 - Elsevier
Functional magnetic resonance imaging (fMRI) has allowed the noninvasive study of task-
based and resting-state brain dynamics in humans by inferring neural activity from blood …

[HTML][HTML] Impact of anesthesia on static and dynamic functional connectivity in mice

T Tsurugizawa, D Yoshimaru - Neuroimage, 2021 - Elsevier
A few studies have compared the static functional connectivity between awake and lightly
anesthetized states in rodents by resting-state fMRI. However, impact of light anesthesia on …

Longitudinal functional magnetic resonance imaging in animal models

AC Silva, JV Liu, Y Hirano, RF Leoni, H Merkle… - … : methods and protocols, 2011 - Springer
Functional magnetic resonance imaging (fMRI) has had an essential role in furthering our
understanding of brain physiology and function. fMRI techniques are nowadays widely …

Functional and pharmacological MRI in understanding brain function at a systems level

A Bifone, A Gozzi - Molecular and Functional Models in Neuropsychiatry, 2011 - Springer
Functional magnetic resonance imaging (fMRI) methods have been extensively applied to
study the human brain and its functional organization in healthy and disease states. A strong …