[HTML][HTML] Malaria disrupts the rhesus macaque gut microbiome

DN Farinella, S Kaur, VL Tran… - Frontiers in Cellular …, 2023 - frontiersin.org
Previous studies have suggested that a relationship exists between severity and
transmissibility of malaria and variations in the gut microbiome, yet only limited information …

Composition of the gut microbiota modulates the severity of malaria

NF Villarino, GR LeCleir, JE Denny… - Proceedings of the …, 2016 - National Acad Sciences
Plasmodium infections result in clinical presentations that range from asymptomatic to
severe malaria, resulting in∼ 1 million deaths annually. Despite this toll on humanity, the …

Altered gastrointestinal tract structure and microbiome following cerebral malaria infection

SA Knowler, A Shindler, JL Wood, A Lakkavaram… - Parasitology …, 2023 - Springer
Cerebral malaria (CM) is the most severe form of malaria with the highest mortality rate and
can result in life-long neurological deficits and ongoing comorbidities. Factors contributing to …

Malaria and the microbiome: a systematic review

MM Ippolito, JE Denny, C Langelier… - Clinical Infectious …, 2018 - academic.oup.com
Background The microbiome influences malaria parasite fitness and transmission efficiency
in mosquitoes and appears to affect malaria dynamics in mammalian hosts as well. Nascent …

[HTML][HTML] Functional Characteristics of the Gut Microbiome in C57BL/6 Mice Differentially Susceptible to Plasmodium yoelii

JMA Stough, SP Dearth, JE Denny… - Frontiers in …, 2016 - frontiersin.org
C57BL/6 mice are widely used for in vivo studies of immune function and metabolism in
mammals. In a previous study, it was observed that when C57BL/6 mice purchased from …

[HTML][HTML] Differential Sensitivity to Plasmodium yoelii Infection in C57BL/6 Mice Impacts Gut-Liver Axis Homeostasis

JE Denny, JB Powers, HF Castro, J Zhang… - Scientific reports, 2019 - nature.com
Experimental models of malaria have shown that infection with specific Plasmodium species
in certain mouse strains can transiently modulate gut microbiota and cause intestinal …

[HTML][HTML] Intestinal injury and the gut microbiota in patients with Plasmodium falciparum malaria

N Sriboonvorakul, K Chotivanich… - PLoS …, 2023 - journals.plos.org
The pathophysiology of severe falciparum malaria involves a complex interaction between
the host, parasite, and gut microbes. In this review, we focus on understanding parasite …

[HTML][HTML] Stool microbiota composition is associated with the prospective risk of Plasmodium falciparum infection

S Yooseph, EF Kirkness, TM Tran, DM Harkins… - BMC genomics, 2015 - Springer
Background In humans it is unknown if the composition of the gut microbiota alters the risk of
Plasmodium falciparum infection or the risk of developing febrile malaria once P. falciparum …

[HTML][HTML] Mechanistic insights into the interaction between the host gut microbiome and malaria

RK Mandal, NW Schmidt - PLoS Pathogens, 2023 - journals.plos.org
Malaria is a devastating infectious disease and significant global health burden caused by
the bite of a Plasmodium-infected female Anopheles mosquito. Gut microbiota was recently …

[HTML][HTML] The dynamic landscape of parasitemia dependent intestinal microbiota shifting and the correlated gut transcriptome during Plasmodium yoelii infection

Z Yawen, C Xiangyun, L Binyou, Y Xingchen… - Microbiological …, 2022 - Elsevier
Malaria, caused by Plasmodium, is a global life-threatening infectious disease. However, the
dynamic interactions between intestinal microbiota and host immunity during the infections …