Background To investigate the role and its potential mechanism of 6-phosphofructo-2-
kinase/fructose-2, 6-bisphosphatase 4 (PFKFB4) in lung adenocarcinoma. Methods Co …

Abstract Phosphofructokinase-2/fructose-2, 6-bisphosphatase 3 (PFKFB3) catalyzes the
synthesis of F2, 6BP, which is an allosteric activator of 6-phosphofructo-1-kinase (PFK-1) …

Background There is growing evidence showing that 6-phosphofructo-2-kinase (PFKFB3)
plays crucial roles in different types of human cancers, including LUAD; however, the …

Background NSCLC (non-small cell lung cancer) has become the malignancy with the
highest incidence and mortality rate worldwide. Fructose-6-phosphate 2-kinase/fructose-2, 6 …

ABSTRACT FGF13, a member of the FGF subfamily, has been found to be highly expressed
in cancer cells such as prostate cancer, melanoma, glioma and multiple myeloma. However …

Objective. To study the expression, biological function, and mechanism of FKBP4 in non‐
small‐cell lung cancer (NSCLC). Methods. First of all, the expression of FKBP4 in NSCLC …

FKBP3 is a member of FK506-binding proteins (FKBPs). Little is known about the expression
and functional role (s) of FKBP3 in non-small cell lung cancer (NSCLC). In the present study …

Phosphofructo 2-kinase/fructose 2, 6-bisphosphatase 3 (PFKFB3) has been reported to be
overexpressed in human cancer tissues and to promote the proliferation and migration of …

Background/Aims: The bi-functional enzyme 6-phosphofructo-2-kinase/fructose-2, 6-
biphosphatase-4 (PFKFB4) is highly expressed in many types of cancer and its requirement …

Background. 6‐Phosphofructo‐2‐kinase/fructose‐2, 6‐biphosphate‐4 (PFKFB4) is a key
factor that plays an important role in tumorigenesis. However, its role in triple‐negative …