Clozapine is widely employed in the treatment of schizophrenia. Compared with that of
atypical first-generation antipsychotics, atypical second-generation antipsychotics such as …

Atypical antipsychotics, such as olanzapine, are commonly prescribed to patients with
schizophrenic symptoms and other psychiatric disorders. However, weight gain and …

Risperidone, a second-generation antipsychotic drug used for schizophrenia treatment with
less-severe side effects, has recently been applied in major depressive disorder treatment …

Doxepin is commonly prescribed for depression and anxiety treatment. Doxepin-related
disruptions to metabolism and renal/hepatic adverse effects remain unclear; thus, the …

Obesity-associated hyperglycemia underlies insulin resistance, glucose intolerance, and
related metabolic disorders including type 2 diabetes, renal damage, and nonalcoholic fatty …

Hepatic steatosis is the accumulation of excess fat in the liver. Recently, hepatic steatosis
has become more important because it occurs in the patients with obesity, type 2 diabetes …

Background Metabolic syndrome (MetS) is a constellation of factors including abdominal
obesity, hyperglycemia, dyslipidemias, and hypertension that increase morbidity and …

Background/Aims: The Zucker diabetic fatty (ZDF, FA/FA) rat is a genetic model of type 2
diabetes, characterized by insulin resistance with progressive metabolic syndrome. We have …

Hyperuricemia has been recognized as a risk factor for insulin resistance as well as one of
the factors leading to diabetic kidney disease (DKD). Since DKD is the most common cause …

The treatment of type 2 diabetes patients with bromocriptine-QR, a unique, quick release
micronized formulation of bromocriptine, improves glycemic control and reduces adverse …