Various RNA-binding proteins (RBPs) are key components in RNA metabolism and
contribute to several neurodevelopmental disorders. To date, only a few of such RBPs have …

The human neocortex is undoubtedly considered a supreme accomplishment in mammalian
evolution. It features a prenatally established six-layered structure which remains plastic to …

Diverse cell types in the central nervous system (CNS) are generated by a relatively small
pool of neural stem cells during early development. Spatial and temporal regulation of stem …

Cortical neurogenesis is a fundamental process of brain development that is
spatiotemporally regulated by both intrinsic and extrinsic cues. Although recent evidence …

RNA-binding motif 8A (RBM8A) is a core component of the exon junction complex (EJC) that
binds pre-mRNAs and regulates their splicing, transport, translation, and nonsense …

The RNA-binding motif 4 (RBM4) protein participates in cell differentiation via its role in
regulating the expression of tissue-specific or developmentally regulated mRNA splice …

RNA regulation contributes to the multiple biological processes adjusting the proper timing
and location of the molecules to be translated. Recent studies have revealed sophisticated …

The role of RNA Binding Motif Protein 8a (RBM8A), an exon junction complex (EJC)
component, in neurodevelopmental disorders has been increasingly studied for its crucial …

Background In eukaryotic cells, RNA-binding proteins (RBPs) contribute to gene expression
by regulating the form, abundance, and stability of both coding and non-coding RNA. In the …

The mammalian cerebral cortex is a complex brain structure integral to our higher cognition.
During embryonic cortical development, radial glial progenitors (RGC s) produce neurons …