Atherosclerosis is an inflammatory and multifaceted disorder resulting from the accumulation
of lipid droplets and several types of immune cells, including macrophages, T and B …

Introduction: A large body of evidence supports the inflammatory hypothesis of
atherosclerosis, and both innate and adaptive immune responses play important roles in all …

Atherosclerosis is an inflammatory disease in which a systemic inflammatory reaction is
combined with an accumulation of immune cells, such as monocytes/macrophages …

Chronic inflammation drives the development of atherosclerosis, and adaptive immunity is
deeply involved in this process. Initial studies attributed a pathogenic role to T cells in …

Cardiovascular disease is the leading cause of death in several countries. The underlying
process is atherosclerosis, a slowly progressing chronic disorder that can lead to …

Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …

Atherosclerotic lesion-related thrombosis is the major cause of myocardial infarction and
stroke, which together constitute the leading cause of mortality worldwide. The inflammatory …

Initiation and progression of atherosclerosis depend on local inflammation and
accumulation of lipids in the vascular wall. Although many cells are involved in the …

Atherosclerosis and related complications still represent the major cause of morbidity and
mortality in the western world. The mechanisms that govern the progression and …

Macrophage accumulation within the vascular wall is a hallmark of atherosclerosis. In
atherosclerotic lesions, macrophages respond to various environmental stimuli, such as …