[HTML][HTML] Interaction between hippocampal-prefrontal plasticity and thalamic-prefrontal activity

LS Bueno-Junior, JE Peixoto-Santos, RN Ruggiero… - Scientific Reports, 2018 - nature.com
The prefrontal cortex integrates a variety of cognition-related inputs, either unidirectional, eg,
from the hippocampal formation, or bidirectional, eg, with the limbic thalamus. While the …

[HTML][HTML] Hippocampal-prefrontal interactions in cognition, behavior and psychiatric disease

T Sigurdsson, S Duvarci - Frontiers in systems neuroscience, 2016 - frontiersin.org
The hippocampus and prefrontal cortex (PFC) have long been known to play a central role
in various behavioral and cognitive functions. More recently, electrophysiological and …

[HTML][HTML] Input convergence, synaptic plasticity and functional coupling across hippocampal-prefrontal-thalamic circuits

LS Bueno-Junior, JP Leite - Frontiers in Neural Circuits, 2018 - frontiersin.org
Executive functions and working memory are long known to involve the prefrontal cortex
(PFC), and two PFC-projecting areas: midline/paramidline thalamus (MLT) and cornus …

Enhanced oscillatory activity in the hippocampal–prefrontal network is related to short-term memory function after early-life seizures

JK Kleen, EX Wu, GL Holmes, RC Scott… - Journal of …, 2011 - Soc Neuroscience
Neurological insults during development are associated with later impairments in learning
and memory. Although remedial training can help restore cognitive function, the neural …

Plasticity at hippocampal to prefrontal cortex synapses: dual roles in working memory and consolidation

S Laroche, S Davis, TM Jay - Hippocampus, 2000 - Wiley Online Library
The involvement of the hippocampus and the prefrontal cortex in cognitive processes and
particularly in learning and memory has been known for a long time. However, the specific …

[HTML][HTML] Prefrontal synaptic activation during hippocampal memory reactivation

Y Nishimura, Y Ikegaya, T Sasaki - Cell Reports, 2021 - cell.com
Cooperative reactivation of hippocampal and prefrontal neurons is considered crucial for
mnemonic processes. To directly record synaptic substances supporting the interregional …

Functional and dysfunctional synaptic plasticity in prefrontal cortex: roles in psychiatric disorders

Y Goto, CR Yang, S Otani - Biological psychiatry, 2010 - Elsevier
Prefrontal cortex (PFC) mediates an assortment of cognitive functions including working
memory, behavioral flexibility, attention, and future planning. Unlike the hippocampus …

[HTML][HTML] Long-term memory, synaptic plasticity and dopamine in rodent medial prefrontal cortex: Role in executive functions

D Sheynikhovich, S Otani, J Bai, A Arleo - Frontiers in Behavioral …, 2023 - frontiersin.org
Mnemonic functions, supporting rodent behavior in complex tasks, include both long-term
and (short-term) working memory components. While working memory is thought to rely on …

[HTML][HTML] Neuromodulation of hippocampal-prefrontal cortical synaptic plasticity and functional connectivity: implications for neuropsychiatric disorders

RN Ruggiero, MT Rossignoli, DB Marques… - Frontiers in cellular …, 2021 - frontiersin.org
The hippocampus-prefrontal cortex (HPC-PFC) pathway plays a fundamental role in
executive and emotional functions. Neurophysiological studies have begun to unveil the …

[HTML][HTML] Dysfunctional hippocampal-prefrontal network underlies a multidimensional neuropsychiatric phenotype following early-life seizure

RN Ruggiero, DB Marques, MT Rossignoli, JB De Ross… - Elife, 2024 - elifesciences.org
Brain disturbances during development can have a lasting impact on neural function and
behavior. Seizures during this critical period are linked to significant long-term …