Prolactin regulates tuberoinfundibular dopamine neuron discharge pattern: novel feedback control mechanisms in the lactotrophic axis
DJ Lyons, A Hellysaz, C Broberger - Journal of Neuroscience, 2012 - Soc Neuroscience
Balance in the body9s hormonal axes depends on feedback onto neuroendocrine
hypothalamic neurons. This phenomenon involves transcriptional and biosynthetic effects …
hypothalamic neurons. This phenomenon involves transcriptional and biosynthetic effects …
Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release
Tuberoinfundibular dopamine (TIDA) neurons are the central regulators of prolactin (PRL)
secretion. Their extensive functional plasticity allows a change from low PRL secretion in the …
secretion. Their extensive functional plasticity allows a change from low PRL secretion in the …
TIDAL WAVES: Network mechanisms in the neuroendocrine control of prolactin release
DJ Lyons, C Broberger - Frontiers in neuroendocrinology, 2014 - Elsevier
Neuroendocrine tuberoinfundibular dopamine (TIDA) neurons tonically inhibit pituitary
release of the hormone, prolactin. Through the powerful actions of prolactin in promoting …
release of the hormone, prolactin. Through the powerful actions of prolactin in promoting …
Synchronized network oscillations in rat tuberoinfundibular dopamine neurons: switch to tonic discharge by thyrotropin-releasing hormone
DJ Lyons, E Horjales-Araujo, C Broberger - Neuron, 2010 - cell.com
The pituitary hormone, prolactin, triggers lactation in nursing mothers. Under nonlactating
conditions, prolactin secretion is suppressed by powerful inhibition from hypothalamic …
conditions, prolactin secretion is suppressed by powerful inhibition from hypothalamic …
Low dose of dopamine may stimulate prolactin secretion by increasing fast potassium currents
J Tabak, N Toporikova, ME Freeman… - Journal of computational …, 2007 - Springer
Dopamine (DA) released from the hypothalamus tonically inhibits pituitary lactotrophs. DA
(at micromolar concentration) opens potassium channels, hyperpolarizing the lactotrophs …
(at micromolar concentration) opens potassium channels, hyperpolarizing the lactotrophs …
Dopamine release dynamics in the tuberoinfundibular dopamine system
The relationship between neuronal impulse activity and neurotransmitter release remains
elusive. This issue is especially poorly understood in the neuroendocrine system, with its …
elusive. This issue is especially poorly understood in the neuroendocrine system, with its …
Excitation of tuberoinfundibular dopamine neurons by oxytocin: crosstalk in the control of lactation
V Briffaud, P Williams, J Courty… - Journal of …, 2015 - Soc Neuroscience
Milk production in the nursing mother is induced by the hormone prolactin. Its release from
the anterior pituitary is generally under tonic inhibition by neuroendocrine tuberoinfundibular …
the anterior pituitary is generally under tonic inhibition by neuroendocrine tuberoinfundibular …
Differential actions of prolactin on electrical activity and intracellular signal transduction in hypothalamic neurons
In many tissues, including brain, prolactin action is predominantly mediated by the Janus
kinase/signal transducer and activator of transcription (STAT) signal transduction pathway …
kinase/signal transducer and activator of transcription (STAT) signal transduction pathway …
Plasticity of the prolactin (PRL) axis: mechanisms underlying regulation of output in female mice
PR Le Tissier, DJ Hodson, AO Martin… - Recent Advances in …, 2015 - Springer
The output of prolactin (PRL) is highly dynamic with dramatic changes in its secretion from
the anterior pituitary gland depending on prevailing physiological status. In adult female …
the anterior pituitary gland depending on prevailing physiological status. In adult female …
Elevated prolactin during pregnancy drives a phenotypic switch in mouse hypothalamic dopaminergic neurons
Altered physiological states require neuronal adaptation. In late pregnancy and lactation, a
sub-population of the mouse hypothalamic tuberoinfundibular dopaminergic (TIDA) neurons …
sub-population of the mouse hypothalamic tuberoinfundibular dopaminergic (TIDA) neurons …