Dilated cardiomyopathy: genetic determinants and mechanisms
EM McNally, L Mestroni - Circulation research, 2017 - Am Heart Assoc
Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …
Familial dilated cardiomyopathy
Advances in human genome sequencing have re-invigorated genetics studies of dilated
cardiomyopathy (DCM), facilitating genetic testing and clinical applications. With a range of …
cardiomyopathy (DCM), facilitating genetic testing and clinical applications. With a range of …
Implications of genetic testing in dilated cardiomyopathy
JAJ Verdonschot, MR Hazebroek… - Circulation: Genomic …, 2020 - Am Heart Assoc
Background: Genetic analysis is a first-tier test in dilated cardiomyopathy (DCM). Electrical
phenotypes are common in genetic DCM, but their exact contribution to the clinical course …
phenotypes are common in genetic DCM, but their exact contribution to the clinical course …
Dilated cardiomyopathy: the complexity of a diverse genetic architecture
Remarkable progress has been made in understanding the genetic basis of dilated
cardiomyopathy (DCM). Rare variants in> 30 genes, some also involved in other …
cardiomyopathy (DCM). Rare variants in> 30 genes, some also involved in other …
Genetics of dilated cardiomyopathy
D Fatkin, R Otway, Z Richmond - Heart Failure Clinics, 2010 - heartfailure.theclinics.com
Dilated cardiomyopathy (DCM) is a myocardial disorder defined by ventricular chamber
enlargement and systolic dysfunction that can result in progressive heart failure …
enlargement and systolic dysfunction that can result in progressive heart failure …
[HTML][HTML] Clinical and genetic issues in dilated cardiomyopathy: a review for genetics professionals
RE Hershberger, A Morales, JD Siegfried - Genetics in Medicine, 2010 - Elsevier
Dilated cardiomyopathy (DCM), usually diagnosed as idiopathic dilated cardiomyopathy
(IDC), has been shown to have a familial basis in 20–35% of cases. Genetic studies in …
(IDC), has been shown to have a familial basis in 20–35% of cases. Genetic studies in …
The complex and diverse genetic architecture of dilated cardiomyopathy
RE Hershberger, J Cowan, E Jordan… - Circulation …, 2021 - Am Heart Assoc
Our insight into the diverse and complex nature of dilated cardiomyopathy (DCM) genetic
architecture continues to evolve rapidly. The foundations of DCM genetics rest on marked …
architecture continues to evolve rapidly. The foundations of DCM genetics rest on marked …
Association of genetic variants with outcomes in patients with nonischemic dilated cardiomyopathy
L Escobar-Lopez, JP Ochoa, JG Mirelis… - Journal of the American …, 2021 - jacc.org
Background The clinical relevance of genetic variants in nonischemic dilated
cardiomyopathy (DCM) is unsettled. Objectives The study sought to assess the prognostic …
cardiomyopathy (DCM) is unsettled. Objectives The study sought to assess the prognostic …
[HTML][HTML] Dilated cardiomyopathy overview
RE Hershberger, E Jordan - 2022 - europepmc.org
Dilated Cardiomyopathy Overview - Abstract - Europe PMC Sign in | Create an account https://orcid.org
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Europe PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter …
Genetic risk of arrhythmic phenotypes in patients with dilated cardiomyopathy
M Gigli, M Merlo, SL Graw, G Barbati… - Journal of the American …, 2019 - jacc.org
Background: Genotype-phenotype correlations in dilated cardiomyopathy (DCM) and, in
particular, the effects of gene variants on clinical outcomes remain poorly understood …
particular, the effects of gene variants on clinical outcomes remain poorly understood …