Ultrafast timing enables reconstruction-free positron emission imaging

SI Kwon, R Ota, E Berg, F Hashimoto, K Nakajima… - Nature …, 2021 - nature.com
X-ray and gamma-ray photons are widely used for imaging but require a mathematical
reconstruction step, known as tomography, to produce cross-sectional images from the …

Time of flight in perspective: instrumental and computational aspects of time resolution in positron emission tomography

DR Schaart, G Schramm, J Nuyts… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
The first time-of-flight positron emission tomography (TOF-PET) scanners were developed
as early as in the 1980s. However, the poor light output and low detection efficiency of TOF …

Photon time-of-flight-assisted positron emission tomography

MM Ter-Pogossian, NA Mullani, DC Ficke… - Journal of computer …, 1981 - journals.lww.com
In positron emission tomography (PET), the annihilation radiation is usually detected as a
coincidence occurrence that localizes the position of the annihilation event to a straight line …

Direct time-of-flight for quantitative, real-time in-beam PET: a concept and feasibility study

P Crespo, G Shakirin, F Fiedler… - Physics in Medicine …, 2007 - iopscience.iop.org
We extrapolate the impact of recent detector and scintillator developments, enabling sub-
nanosecond coincidence timing resolution (τ), onto in-beam positron emission tomography …

Studies on the Cherenkov effect for improved time resolution of TOF-PET

SE Brunner, L Gruber, J Marton… - IEEE Transactions on …, 2013 - ieeexplore.ieee.org
With the newly gained interest in the time-of-flight method for positron emission tomography
(TOF-PET), many options for pushing the time resolution to its borders have been …

Photo-detectors for time of flight positron emission tomography (ToF-PET)

VC Spanoudaki, CS Levin⋆ - Sensors, 2010 - mdpi.com
We present the most recent advances in photo-detector design employed in time of flight
positron emission tomography (ToF-PET). PET is a molecular imaging modality that collects …

Coincidence time resolution of 30 ps FWHM using a pair of Cherenkov-radiator-integrated MCP-PMTs

R Ota, K Nakajima, I Ogawa… - Physics in Medicine …, 2019 - iopscience.iop.org
Radiation detectors dedicated to time-of-flight positron emission tomography (PET) have
been developed, and coincidence time resolution (CTR) of sub-100 ps full width at half …

Tofpet asic for pet applications

MD Rolo, R Bugalho, F Goncalves… - Journal of …, 2013 - iopscience.iop.org
A 64-channel ASIC for Time-of-Flight Positron Emission Tomography (TOF PET) imaging
has been designed and simulated. The circuit is optimized for the readout of signals …

Subsecond total-body imaging using ultrasensitive positron emission tomography

X Zhang, SR Cherry, Z Xie, H Shi… - Proceedings of the …, 2020 - National Acad Sciences
A 194-cm-long total-body positron emission tomography/computed tomography (PET/CT)
scanner (uEXPLORER), has been constructed to offer a transformative platform for human …

Using convolutional neural networks to estimate time-of-flight from PET detector waveforms

E Berg, SR Cherry - Physics in Medicine & Biology, 2018 - iopscience.iop.org
Although there have been impressive strides in detector development for time-of-flight
positron emission tomography, most detectors still make use of simple signal processing …