Background To determine the prognostic value of Src homology 2 domain-containing
transforming protein C3 (SHC3) in colorectal cancer (CRC). Methods The pan-cancer …

Abstract Background The Src homology and collagen 4 (SHC4) is an important intracellular
adaptor protein that has been shown to play a pro-cancer role in melanoma and glioma …

Background: Recent studies highlight the carcinogenesis role of SHC-adaptor protein 1
(SHC1) in cancer initiation, development, and progression. However, its aberrant …

Simple Summary SH3 domain and tetrapeptide repeat 2 (SH3TC2) is a protein-encoding
gene and has previously been described as a critical signaling hub for neurological …

Background & Aims The tumor-suppressor sterile α motif–and Src-homology 3–domain
containing 1 (SASH1) has clinical relevance in colorectal carcinoma and is associated …

The adaptor protein Srcin1 is a novel Src-binding protein that regulates Src activation
through C-terminal Src kinase (Csk). Srcin1 behaves as a tumour suppressor in breast …

Abstract Slingshot phosphatase 3 (SSH3) is a member of the SSH phosphatase family that
regulates actin filament dynamics. However, its role in cancer metastasis is relatively unclear …

Invasion and intrahepatic metastasis are major factors of poor prognosis in patients with
hepatocellular carcinoma (HCC). In this study, we show that increased Src homolog and …

Shc protein is known to be related to cell proliferation and carcinogenesis. However, the
involvement of Shc in gastric cancer remains unknown. In the present study, we examined …

The study aims to explore the biological function of SHC1 in the development and
progression of lung cancer. Meanwhile, the effect of SHC1 and EGFR on lung cancer was …