Background Respiratory diseases are one of the leading causes of death worldwide, yet
effective treatment options remain limited. Although inflammation is thought to be a key …

Lung inflammatory diseases contribute significantly to the socioeconomic burden of disease.
Yet very few new, effective therapies for respiratory disease have been approved for use. A …

Inflammatory lung disease is one of the most common clinical scenarios, and yet, it is often
poorly understood. Inflammatory lung disorders, such as chronic obstructive pulmonary …

Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …

Methods currently used to assess lung and airway inflammation are often poorly
quantitative, invasive, nonspecific, or insensitive. Positron emission tomography (PET) with …

This review focuses on methods to image acute lung inflammation with Positron Emission
Tomography (PET). Four approaches are discussed that differ for biologic function of the …

Background An inflammatory reaction in the airways and lung parenchyma, comprised
mainly of neutrophils and alveolar macrophages, is present in some patients with chronic …

PET with 18F-FDG has been increasingly applied, predominantly in the research setting, to
study drug effects and pulmonary biology and to monitor disease progression and treatment …

Acute and chronic lung diseases are almost invariably associated with some degree of
inflammation. Cells that evolved as an effective mechanism to counter infection and heal …

Positron emission tomography (PET) is a quantitative molecular imaging modality
increasingly used to study pulmonary disease processes and drug effects on those …