OBJECTIVES: Takayasu's arteritis (TAK) involves inflammatory vasculitis of large vessels
and mainly affects the aorta and its major branches. Abnormal immunity may play a vital role …

Background Takayasu's arteritis (TA) is a type of primary large vessel vasculitis. Th1, Th17,
and Tfh cells have been reported to be associated with TA relapse. However, the …

Objective T cell-mediated immune response plays a key role in Takayasu arteritis (TAK).
Although previous studies have showed the roles of CD4+ T cell and its subsets in TAK, the …

Objective. To investigate T cell subsets and immune cytokine profiles in untreated Takayasu
arteritis (TAK) patients and the underlying immunopathological mechanism. Methods. We …

Takayasu's arteritis (TAK) is a type of large vessel vasculitis which involves the aorta and its
major branches. Interleukin (IL)-9 or IL-9-producing Th9 cells were found to be involved in …

Objective Takayasu arteritis (TAK) is a large‐vessel vasculitis that induces damage to the
aorta and its branches. Glucocorticoids remain the gold standard of therapy for TAK. The …

We have investigated intracellular production by T cells and plasma levels of TNF-α, IL-2
and IFN-γ in 12 active and 10 inactive Takayasu's arteritis (TA) patients and 12 healthy …

We studied T-cell receptor (TCR) repertoire of circulating gamma delta (γδ) T-cells in 20
patients with Takayasu's arteritis (TA), 20 healthy controls (HC), 7 follow up TA patients, and …

Purpose We evaluated T helper lymphocyte profile, including novel Th17 subsets Th17. 1
(secrete IFN-γ, associate with corticosteroid resistance) and PD1+ Th17 (secrete TGF-β1 …

To further investigate the immunological mechanisms involved in Takayasu's arteritis, we
analyzed the T-cell receptor (TCR) Vγ and Vδ gene usage by infiltrating γδ T-cells and the …