[HTML][HTML] Cofilin1-dependent actin dynamics control DRP1-mediated mitochondrial fission

K Rehklau, L Hoffmann, CB Gurniak, M Ott… - Cell death & …, 2017 - nature.com
Mitochondria form highly dynamic networks in which organelles constantly fuse and divide.
The relevance of mitochondrial dynamics is evident from its implication in various human …

[PDF][PDF] Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission

KJ De Vos, VJ Allan, AJ Grierson, MP Sheetz - Current Biology, 2005 - cell.com
Mitochondria display a variety of shapes, ranging from small and spherical or the classical
tubular shape to extended networks [1, 2]. Shape transitions occur frequently and include …

A role for septin 2 in Drp1‐mediated mitochondrial fission

A Pagliuso, TN Tham, JK Stevens, T Lagache… - EMBO …, 2016 - embopress.org
Mitochondria are essential eukaryotic organelles often forming intricate networks. The
overall network morphology is determined by mitochondrial fusion and fission. Among the …

Actin (g) on mitochondria–a role for cofilin1 in neuronal cell death pathways

L Hoffmann, MB Rust, C Culmsee - Biological chemistry, 2019 - degruyter.com
Actin dynamics, the coordinated assembly and disassembly of actin filaments (F-actin), are
essential for fundamental cellular processes, including cell shaping and motility, cell division …

[PDF][PDF] A role for myosin II in mammalian mitochondrial fission

F Korobova, TJ Gauvin, HN Higgs - Current Biology, 2014 - cell.com
Mitochondria are dynamic organelles, undergoing both fission and fusion regularly in
interphase cells. Mitochondrial fission is thought to be part of a quality-control mechanism …

[HTML][HTML] Recent advances into the understanding of mitochondrial fission

K Elgass, J Pakay, MT Ryan, CS Palmer - Biochimica et Biophysica Acta …, 2013 - Elsevier
Mitochondria exist as a highly dynamic tubular network, and their morphology is governed
by the delicate balance between frequent fusion and fission events, as well as by …

Novel roles for actin in mitochondrial fission

AL Hatch, PS Gurel, HN Higgs - Journal of cell science, 2014 - journals.biologists.com
Mitochondrial dynamics, including fusion, fission and translocation, are crucial to cellular
homeostasis, with roles in cellular polarity, stress response and apoptosis. Mitochondrial …

Mitochondrial fission and mitophagy depend on cofilin-mediated actin depolymerization activity at the mitochondrial fission site

GB Li, HW Zhang, RQ Fu, XY Hu, L Liu, YN Li, YX Liu… - Oncogene, 2018 - nature.com
Mitochondria fission and mitophagy are fundamentally crucial to cellular physiology and
play important roles in cancer progression. Developing a comprehensive understanding of …

Mitochondrial network structure homeostasis and cell death

L Xie, F Shi, Z Tan, Y Li, AM Bode, Y Cao - Cancer science, 2018 - Wiley Online Library
Mitochondria are the major cellular energy‐producing organelles and intracellular source of
reactive oxygen species. These organelles are responsible for driving cell life and death …

Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission

S Li, S Xu, BA Roelofs, L Boyman, WJ Lederer… - Journal of Cell …, 2015 - rupress.org
In addition to established membrane remodeling roles in various cellular locations, actin has
recently emerged as a participant in mitochondrial fission. However, the underlying …