While functions of the gastrointestinal (GI) microbiome include maintenance of immune
homeostasis and protection against infectious disease, its role in determining disease …

Plasmodium infections result in clinical presentations that range from asymptomatic to
severe malaria, resulting in∼ 1 million deaths annually. Despite this toll on humanity, the …

Gut microbiota composition is associated with human and rodent Plasmodium infections, yet
the mechanism by which gut microbiota affects the severity of malaria remains unknown …

Previous studies have suggested that a relationship exists between severity and
transmissibility of malaria and variations in the gut microbiome, yet only limited information …

Plasmodium, the causative agent of malaria, is responsible for more than 200 million new
infections and 400 000 deaths yearly. While in recent years the influence of the microbiota in …

The pathophysiology of severe falciparum malaria involves a complex interaction between
the host, parasite, and gut microbes. In this review, we focus on understanding parasite …

Background In humans it is unknown if the composition of the gut microbiota alters the risk of
Plasmodium falciparum infection or the risk of developing febrile malaria once P. falciparum …

Systems-scale analysis of multiple layers of molecular and cellular data has significant
potential for providing novel insights into malaria pathology and immunity. We present here …

Experimental models of malaria have shown that infection with specific Plasmodium species
in certain mouse strains can transiently modulate gut microbiota and cause intestinal …

Highlights•Gut microbiota is associated with malaria in rodents and humans.•Gut microbiota
influences systemic adaptive immune responses.•Probiotic treatment in infants can …