Estimation of time of HIV seroconversion using a modified CD4 depletion model

VD Lima, L Wang, P Sereda, T McLinden, R Barrios… - PLoS …, 2021 - journals.plos.org
Introduction Several methods have been proposed to estimate the time of HIV
seroconversion, including those based on CD4 cell depletion models. However, previous …

Estimates of the time from seroconversion to antiretroviral therapy initiation among people newly diagnosed with human immunodeficiency virus from 2006 to 2015 …

MKM Robertson, SL Braunstein… - Clinical Infectious …, 2020 - academic.oup.com
Background We estimated the time from human immunodeficiency virus (HIV)
seroconversion to antiretroviral therapy (ART) initiation during an era of expanding HIV …

[HTML][HTML] O212 Rate of change in CD4 counts in patients with stable HIV viremia

AN Phillips, B Ledergerber, JR Bogner… - Journal of the …, 2008 - Springer
Methods Annual CD4 slopes were calculated from three consecutive CD4 measurements
whilst the viral load was stable, defined as< 0.5 log 10 copies/ml difference between the …

Estimation of the duration between HIV seroconversion and HIV diagnosis in different population groups in French Guiana: Strategic information to reduce the …

M Nacher, A Adenis, F Huber, E Hallet, P Abboud… - PLoS …, 2018 - journals.plos.org
Background Given the great efforts put into the strategic objective of reducing the proportion
of HIV-infected patients that are undiagnosed, the aim of the present study was to review the …

Joint estimation of CD4+ cell progression and survival in untreated individuals with HIV-1 infection

TD Mangal - Aids, 2017 - journals.lww.com
Objective: We compiled the largest dataset of seroconverter cohorts to date from 25
countries across Africa, North America, Europe, and Southeast/East (SE/E) Asia to …

Disease progression and mortality with untreated HIV infection: Evidence synthesis of HIV seroconverter cohorts, antiretroviral treatment clinical cohorts and …

R Glaubius, N Kothegal, S Birhanu… - Journal of the …, 2021 - Wiley Online Library
Introduction Model‐based estimates of key HIV indicators depend on past epidemic trends
that are derived based on assumptions about HIV disease progression and mortality in the …

CD4+ cell dynamics in untreated HIV-1 infection: overall rates, and effects of age, viral load, sex and calendar time

A Cori, M Pickles, A van Sighem, L Gras, D Bezemer… - Aids, 2015 - journals.lww.com
Background: CD4+ cell count is a key measure of HIV disease progression, and the basis of
successive international guidelines for treatment initiation. CD4+ cell dynamics are used in …

The rate of CD4 decline as a determinant of progression to AIDS independent of the most recent CD4 count

AC Lepri, CA Sabin, AN Phillips, CA Lee… - Epidemiology & …, 1998 - cambridge.org
The data of two cohort studies of HIV-infected individuals were used to examine whether the
rate of CD4 decline is a determinant of HIV progression, independent of the most recent …

The rate of CD4 decline as a determinant of progression to AIDS independent of the most recent CD4 count. The Italian Seroconversion Study.

CA Sabin, AN Phillips, CA Lee, P Pezzotti… - Epidemiology and …, 1998 - europepmc.org
The data of two cohort studies of HIV-infected individuals were used to examine whether the
rate of CD4 decline is a determinant of HIV progression, independent of the most recent …

Is there a general tendency for CD4 lymphocyte decline to speed up during human immunodeficiency virus infection? Evidence from the Italian Seroconversion Study

AC Lepri, CA Sabin, P Pezzotti… - Journal of Infectious …, 1997 - academic.oup.com
It has been suggested that the rate of CD4 cell decline accelerates in parallel with
decreasing numbers of cells; however, the statistical literature suggests the opposite. CD4 …