Biologics in inflammatory bowel disease: what are the data?

J Côté-Daigneault, M Bouin, R Lahaie… - United European …, 2015 - journals.sagepub.com
Background Over the last decade, biologics have gained an important place for the
treatment of moderate to severe inflammatory bowel disease (IBD), and many randomized …

Biologic therapies in inflammatory bowel disease

LB Cohen, RM Nanau, F Delzor, MG Neuman - Translational Research, 2014 - Elsevier
Inflammatory bowel disease, including its 2 entities ulcerative colitis and Crohn's disease, is
a chronic medical condition characterized by the destructive inflammation of the intestinal …

Adverse effects of biologics used for treating IBD

A Stallmach, S Hagel, T Bruns - Best practice & research Clinical …, 2010 - Elsevier
In the last decade, biologic agents, in particular anti-TNF agents such as infliximab,
adalimumab, and certolizumab have substantially extended the therapeutic armamentarium …

Biologic agents for IBD: practical insights

S Danese, L Vuitton, L Peyrin-Biroulet - … reviews Gastroenterology & …, 2015 - nature.com
Six biologic agents are currently approved for the treatment of IBD: four anti-TNF agents
(infliximab, adalimumab, golimumab and certolizumab pegol) and two anti-integrin agents …

[HTML][HTML] Advances in the development of new biologics in inflammatory bowel disease

B Ungar, U Kopylov - … : quarterly publication of the Hellenic Society …, 2016 - ncbi.nlm.nih.gov
Biologics have revolutionized the therapeutic approach in inflammatory bowel disease
(IBD). Anti-tumor necrosis factor (anti-TNF) agents infliximab and adalimumab currently …

Next-generation therapeutics for IBD

M Löwenberg, G D'Haens - Current gastroenterology reports, 2015 - Springer
Various novel drugs have recently been evaluated in clinical trials showing promising effects
in patients with inflammatory bowel disease (IBD). Here, we summarize the recent literature …

The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to …

GR D'haens, R Panaccione, PDR Higgins… - Official journal of the …, 2011 - journals.lww.com
The advent of biological therapy has revolutionized inflammatory bowel disease (IBD) care.
Nonetheless, not all patients require biological therapy. Selection of patients depends on …

Biological therapies in inflammatory bowel disease: Beyond anti-TNF therapies

KH Katsanos, K Papamichael, JD Feuerstein… - Clinical …, 2019 - Elsevier
The pharmacological management of inflammatory bowel disease (IBD) over the last two
decades has transitioned from reliance on aminosalycilates, corticosteroids and …

Biologics in inflammatory bowel disease: how much progress have we made?

WJ Sandborn, WA Faubion - Gut, 2004 - gut.bmj.com
INTRODUCTION Biologic therapies include:(1) naturally occurring or modified biologic
compounds such as vaccines (live, live attenuated, or killed microorganisms), hormone …

Role of biologics and biosimilars in inflammatory bowel disease: current trends and future perspectives

P Rawla, T Sunkara, JP Raj - Journal of inflammation research, 2018 - Taylor & Francis
Inflammatory bowel disease (IBD) is an idiopathic chronic inflammatory disease of the
gastrointestinal system. The spectrum is of predominantly two types, namely, ulcerative …