The strategy of repeated ketamine in open-label and saline-control studies of treatment-
resistant depression suggested greater antidepressant response beyond a single ketamine …

Objective: Subanesthetic ketamine doses have been shown to have rapid yet transient
antidepressant effects in patients with treatment-resistant depression, which may be …

Objective: Preliminary evidence supports the safety and efficacy of subanesthetic ketamine
as an experimental antidepressant, although its effects are often not sustained beyond one …

BACKGROUND: A single subanesthetic (intravenous) IV dose of ketamine might have rapid
but transient antidepressant effects in patients with treatment-resistant depression (TRD) …

Objective: Ketamine, an N-methyl-d-aspartate glutamate receptor antagonist, has
demonstrated a rapid-onset antidepressant effect in patients with treatment-resistant …

Background Ketamine has been showing high efficacy and rapid antidepressant effect.
However, studies of ketamine infusion wash subjects out from prior antidepressants, which …

Background Ketamine is reported to have rapid antidepressant effects; however, there is
limited understanding of the time-course of ketamine effects beyond a single infusion. A …

Background: Ketamine has a rapid antidepressant effect in treatment-resistant depression
(TRD). The effects on cognitive function of multiple ketamine infusions and of concurrent …

Objectives We examined the feasibility of a high-dose, 96-h infusion of ketamine in treatment-
resistant depression. Methods Ten participants were randomised to receive a 96-h ketamine …

BACKGROUND: Acute administration of subanesthestic doses of intravenous ketamine
have been shown to elicit a rapid antidepressant response in patients with treatment …