Cognitive behavioral therapy to sustain the antidepressant effects of ketamine in treatment-resistant depression: a randomized clinical trial
Introduction: Ketamine has emerged as a rapid-acting antidepressant. While ongoing
treatment can prevent relapse, concerns exist regarding long-term exposure. Objective: We …
treatment can prevent relapse, concerns exist regarding long-term exposure. Objective: We …
Ketamine as a new treatment for depression: a review of its efficacy and adverse effects
N Katalinic, R Lai, A Somogyi… - Australian & New …, 2013 - journals.sagepub.com
Objective: Narrative review of the literature on the efficacy and safety of subanaesthetic
doses of ketamine for the treatment of depression. Method: Medline and PubMed databases …
doses of ketamine for the treatment of depression. Method: Medline and PubMed databases …
Neurocognitive performance of repeated versus single intravenous subanesthetic ketamine in treatment resistant depression
Background Ketamine demonstrated rapid antidepressant effects in treatment-resistant
depression (TRD). However, evaluation of ketamine's neurocognitive effect in TRD is …
depression (TRD). However, evaluation of ketamine's neurocognitive effect in TRD is …
The use of ketamine as an antidepressant: a systematic review and meta‐analysis
CM Coyle, KR Laws - Human Psychopharmacology: Clinical …, 2015 - Wiley Online Library
Objective The current meta‐analysis examines the effects of ketamine infusion on
depressive symptoms over time in major depressive disorder (MDD) and bipolar disorder …
depressive symptoms over time in major depressive disorder (MDD) and bipolar disorder …
Ketamine for Depression—Knowns, Unknowns, Possibilities, Barriers, and Opportunities
C Andrade - JAMA psychiatry, 2023 - jamanetwork.com
Many drugs used in medicine have on-and off-label indications that span different medical
disciplines. Ketamine now has evidence of efficacy for emergency …
disciplines. Ketamine now has evidence of efficacy for emergency …
Effects of low-dose and very low-dose ketamine among patients with major depression: a systematic review and meta-analysis
Background: Several recent trials indicate low-dose ketamine produces rapid
antidepressant effects. However, uncertainty remains in several areas: dose response …
antidepressant effects. However, uncertainty remains in several areas: dose response …
Comprehensive assessment of side effects associated with a single dose of ketamine in treatment-resistant depression
EE Acevedo-Diaz, GW Cavanaugh… - Journal of affective …, 2020 - Elsevier
Background Concerns about ketamine for treating depression include abuse potential and
the occurrence of psychotomimetic effects. This study sought to comprehensively assess …
the occurrence of psychotomimetic effects. This study sought to comprehensively assess …
Concomitant benzodiazepine use attenuates ketamine response: implications for large scale study design and clinical development
MA Frye, P Blier, SJ Tye - Journal of clinical psychopharmacology, 2015 - journals.lww.com
The most recent data from the Global Burden of Disease Study highlight that 47.5%(ie, 183.9
million) of all disability-adjusted life years are attributable to mood disorders with an …
million) of all disability-adjusted life years are attributable to mood disorders with an …
Clinical predictors of ketamine response in treatment-resistant major depression
Objective: The N-methyl-d-aspartate receptor antagonist ketamine has rapid antidepressant
effects in treatment-resistant major depressive disorder (MDD) and bipolar depression …
effects in treatment-resistant major depressive disorder (MDD) and bipolar depression …
A systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials of ketamine in the rapid treatment of major depressive episodes
BackgroundThere is growing interest in glutamatergic agents in depression, particularly
ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist. We aimed to …
ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist. We aimed to …