[HTML][HTML] The evolutionary ecology of dormancy in nature and in cancer
Dormancy is an inactive period of an organism's life cycle that permits it to survive through
phases of unfavorable conditions in highly variable environments. Dormancy is not binary …
phases of unfavorable conditions in highly variable environments. Dormancy is not binary …
Tumor dormancy and relapse: from a natural byproduct of evolution to a disease state
MH Manjili - Cancer research, 2017 - AACR
Species evolve by mutations and epigenetic changes acting on individuals in a population;
tumors evolve by similar mechanisms at a cellular level in a tissue. This article reviews …
tumors evolve by similar mechanisms at a cellular level in a tissue. This article reviews …
[HTML][HTML] Tumor dormancy: implications for invasion and metastasis
Tumor dormancy refers to a critical stage of cancer development when tumor cells are
present, but cancer does not progress. It includes both the concept of cellular dormancy …
present, but cancer does not progress. It includes both the concept of cellular dormancy …
Tumor dormancy as an alternative step in the development of chemoresistance and metastasis-clinical implications
F Rossari, C Zucchinetti, G Buda, E Orciuolo - Cellular Oncology, 2020 - Springer
Background The ability of a tumor to become dormant in response to suboptimal conditions
has recently been recognized as a key step in tumor progression. Tumor dormancy has …
has recently been recognized as a key step in tumor progression. Tumor dormancy has …
The problem of cancer dormancy: understanding the basic mechanisms and identifying therapeutic opportunities
JA Aguirre-Ghiso - Cell Cycle, 2006 - Taylor & Francis
The hiatus observed in the progression of cancer after diagnosis and treatment in a large
proportion of patients has led to the notion that a state of cancer dormancy must exist during …
proportion of patients has led to the notion that a state of cancer dormancy must exist during …
Pattern recognition of tumor dormancy and relapse beyond cell-intrinsic and cell-extrinsic pathways
MH Manjili, K Khazaie - Seminars in Cancer Biology, 2022 - Elsevier
In this thematic issue, several mechanisms of tumor dormancy and relapse are discussed.
The reviews suggest mutual interactions and communications between malignant cells and …
The reviews suggest mutual interactions and communications between malignant cells and …
Mechanisms of cancer cell dormancy—another hallmark of cancer?
AC Yeh, S Ramaswamy - Cancer research, 2015 - AACR
Disease relapse in cancer patients many years after clinical remission, often referred to as
cancer dormancy, is well documented but remains an incompletely understood …
cancer dormancy, is well documented but remains an incompletely understood …
The dormant cancer cell life cycle
TG Phan, PI Croucher - Nature Reviews Cancer, 2020 - nature.com
The success of targeted therapies and immunotherapies has created optimism that cancers
may be curable. However, not all patients respond, drug resistance is common and many …
may be curable. However, not all patients respond, drug resistance is common and many …
[HTML][HTML] Tumor cell dormancy: threat or opportunity in the fight against cancer
R Jahanban-Esfahlan, K Seidi, MH Manjili… - Cancers, 2019 - mdpi.com
Tumor dormancy, a clinically undetectable state of cancer, makes a major contribution to the
development of multidrug resistance (MDR), minimum residual disease (MRD), tumor …
development of multidrug resistance (MDR), minimum residual disease (MRD), tumor …
[PDF][PDF] Cancer dormancy from mice to man: A review
R Marches, R Scheuermann, J Uhr - Cell Cycle, 2006 - Taylor & Francis
Cancer Dormancy from Mice to Man: A Review Page 1 ©2006 LANDES BIOSCIENCE. DO NOT
DISTRIBUTE. [Cell Cycle 5:16, 1772-1778, 15 August 2006]; ©2006 Landes Bioscience 1772 …
DISTRIBUTE. [Cell Cycle 5:16, 1772-1778, 15 August 2006]; ©2006 Landes Bioscience 1772 …