[HTML][HTML] The evolutionary ecology of dormancy in nature and in cancer

AK Miller, JS Brown, H Enderling, D Basanta… - Frontiers in Ecology …, 2021 - frontiersin.org
Dormancy is an inactive period of an organism's life cycle that permits it to survive through
phases of unfavorable conditions in highly variable environments. Dormancy is not binary …

Tumor dormancy and relapse: from a natural byproduct of evolution to a disease state

MH Manjili - Cancer research, 2017 - AACR
Species evolve by mutations and epigenetic changes acting on individuals in a population;
tumors evolve by similar mechanisms at a cellular level in a tissue. This article reviews …

[HTML][HTML] Tumor dormancy: implications for invasion and metastasis

G Gomatou, N Syrigos, IA Vathiotis… - International journal of …, 2021 - mdpi.com
Tumor dormancy refers to a critical stage of cancer development when tumor cells are
present, but cancer does not progress. It includes both the concept of cellular dormancy …

Tumor dormancy as an alternative step in the development of chemoresistance and metastasis-clinical implications

F Rossari, C Zucchinetti, G Buda, E Orciuolo - Cellular Oncology, 2020 - Springer
Background The ability of a tumor to become dormant in response to suboptimal conditions
has recently been recognized as a key step in tumor progression. Tumor dormancy has …

The problem of cancer dormancy: understanding the basic mechanisms and identifying therapeutic opportunities

JA Aguirre-Ghiso - Cell Cycle, 2006 - Taylor & Francis
The hiatus observed in the progression of cancer after diagnosis and treatment in a large
proportion of patients has led to the notion that a state of cancer dormancy must exist during …

Pattern recognition of tumor dormancy and relapse beyond cell-intrinsic and cell-extrinsic pathways

MH Manjili, K Khazaie - Seminars in Cancer Biology, 2022 - Elsevier
In this thematic issue, several mechanisms of tumor dormancy and relapse are discussed.
The reviews suggest mutual interactions and communications between malignant cells and …

Mechanisms of cancer cell dormancy—another hallmark of cancer?

AC Yeh, S Ramaswamy - Cancer research, 2015 - AACR
Disease relapse in cancer patients many years after clinical remission, often referred to as
cancer dormancy, is well documented but remains an incompletely understood …

The dormant cancer cell life cycle

TG Phan, PI Croucher - Nature Reviews Cancer, 2020 - nature.com
The success of targeted therapies and immunotherapies has created optimism that cancers
may be curable. However, not all patients respond, drug resistance is common and many …

[HTML][HTML] Tumor cell dormancy: threat or opportunity in the fight against cancer

R Jahanban-Esfahlan, K Seidi, MH Manjili… - Cancers, 2019 - mdpi.com
Tumor dormancy, a clinically undetectable state of cancer, makes a major contribution to the
development of multidrug resistance (MDR), minimum residual disease (MRD), tumor …

[PDF][PDF] Cancer dormancy from mice to man: A review

R Marches, R Scheuermann, J Uhr - Cell Cycle, 2006 - Taylor & Francis
Cancer Dormancy from Mice to Man: A Review Page 1 ©2006 LANDES BIOSCIENCE. DO NOT
DISTRIBUTE. [Cell Cycle 5:16, 1772-1778, 15 August 2006]; ©2006 Landes Bioscience 1772 …