Ca2+-Sensing Receptor (CaSR)

G Valenti - Encyclopedia of Molecular Pharmacology, 2022 - Springer
Ca2+ is an important intracellular second messenger that controls several cellular functions
including muscle contraction in smooth and cardiac muscle. Ca2+ channel blockers (“Ca2+ …

Ca2+ Channel Blockers

J Striessnig, NJ Ortner - Encyclopedia of Molecular Pharmacology, 2022 - Springer
Ca2+ is an important intracellular second messenger that controls several cellular functions
including muscle contraction in smooth and cardiac muscle. Ca2+ channel blockers (“Ca2+ …

Pharmacological basis of Ca2+ channels and Ca2+ channel antagonists

S Adachi-Akahane - Clinical Calcium, 2005 - europepmc.org
Ca2+ plays multiple roles in muscle EC coupling, secretion, and neural transmission, in
addition to survival, proliferation, and death of cells. The voltage-dependent L-type Ca2+ …

[HTML][HTML] International Union of Basic and Clinical Pharmacology XXX: Calcium-sensing receptor Nomenclature, Pharmacology, and Function

L Katie, MH Fadil, MJ Tracy, NK Andrew… - Pharmacological …, 2020 - ncbi.nlm.nih.gov
The calcium-sensing receptor (CaSR) is a class CG protein-coupled receptor (GPCR) that
responds to multiple endogenous agonists and allosteric modulators, including di-and tri …

International union of basic and clinical pharmacology. CVIII. Calcium-sensing receptor nomenclature, pharmacology, and function

K Leach, FM Hannan, TM Josephs, AN Keller… - Pharmacological …, 2020 - ASPET
The calcium-sensing receptor (CaSR) is a class CG protein–coupled receptor that responds
to multiple endogenous agonists and allosteric modulators, including divalent and trivalent …

Agonists and allosteric modulators of the calcium-sensing receptor and their therapeutic applications

Z Saidak, M Brazier, S Kamel, R Mentaverri - Molecular pharmacology, 2009 - ASPET
The calcium-sensing receptor (CaR) belongs to the G protein-coupled receptor superfamily,
with a characteristic structure consisting of seven transmembrane helices, an intracellular C …

Calcium-sensing receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

D Bikle, H Bräuner-Osborne, EM Brown… - IUPHAR/BPS Guide …, 2019 - journals.ed.ac.uk
The calcium-sensing receptor (CaS, provisional nomenclature as recommended by NC-
IUPHAR [44]) responds to multiple endogenous ligands, including extracellular calcium and …

Calcium-sensing receptor (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database

D Bikle, H Bräuner-Osborne, EM Brown… - IUPHAR/BPS Guide …, 2020 - journals.ed.ac.uk
The calcium-sensing receptor (CaS, provisional nomenclature as recommended by NC-
IUPHAR [46] and subsequently updated [76]) responds to multiple endogenous ligands …

[HTML][HTML] Calcium sensing receptor expression and signalling in cardiovascular physiology and disease

R Schreckenberg, KD Schlüter - Vascular pharmacology, 2018 - Elsevier
Initially identified in the parathyroidea, the calcium sensing receptor (CaSR) is now
recognized as an ubiquitously expressed receptor that exerts specific functions in multiple …

Calcium-sensing receptors, biology, and clinical significance: a systemic review

AR Tawfeek, AZ Galal, KS Mostafa… - Menoufia Medical …, 2013 - menoufia-med-j.com
This is a study of calcium-sensing receptors (CaSR), biology, and clinical significance. The
CaSR plays an essential role in the regulation of extracellular calcium (Ca 2+) homeostasis …