Advances in dendritic cell targeting nano-delivery systems for induction of immune tolerance

G Lin, J Wang, YG Yang, Y Zhang… - Frontiers in Bioengineering …, 2023 - frontiersin.org
Dendritic cells (DCs) are the major specialized antigen-presenting cells (APCs), play a key
role in initiating the body's immune response, maintain the balance of immunity. DCs can …

Nanoparticle-based drug delivery systems for induction of tolerance and treatment of autoimmune diseases

H Li, YG Yang, T Sun - Frontiers in bioengineering and biotechnology, 2022 - frontiersin.org
Autoimmune disease is a chronic inflammatory disease caused by disorders of immune
regulation. Antigen-specific immunotherapy has the potential to inhibit the autoreactivity of …

Nanotechnology-based manipulation of dendritic cells for enhanced immunotherapy strategies

R Klippstein, D Pozo - Nanomedicine: Nanotechnology, Biology and …, 2010 - Elsevier
Dendritic cells (DCs) are potent antigen-presenting cells capable of initiating a primary
immune response and possess the ability to activate T cells and stimulate the growth and …

Inducing immune tolerance with dendritic cell-targeting nanomedicines

A Cifuentes-Rius, A Desai, D Yuen… - Nature …, 2021 - nature.com
Induced tolerogenic dendritic cells are a powerful immunotherapy for autoimmune disease
that have shown promise in laboratory models of disease and early clinical trials. In contrast …

Recent advances in nanotechnology for dendritic cell-based immunotherapy

C Qian, LJ Yang, H Cui - Frontiers in Pharmacology, 2020 - frontiersin.org
Dendritic cells (DCs) are the most important antigen-presenting cells that determine cancer
immune responses by regulating immune activation and tolerance, especially in the …

Nanoparticles for dendritic cell-based immunotherapy

TH Tran, TTP Tran, HT Nguyen, C Dai Phung… - International journal of …, 2018 - Elsevier
Crosstalk among immune cells has attracted considerable attention with the advent of
immunotherapy as a novel therapeutic approach for challenging diseases, especially …

Biodegradable nanoparticle mediated antigen delivery to human cord blood derived dendritic cells for induction of primary T cell responses

M Diwan, P Elamanchili, H Lane, A Gainer… - Journal of Drug …, 2003 - Taylor & Francis
Dendritic cells (DCs) in the peripheral tissues act as sentinels of the immune system. They
detect and capture pathogens entering the body and present their antigens to T cells to …

Biomimetic nanoparticles for DC vaccination: a versatile approach to boost cancer immunotherapy

L Meng, Z Teng, S Yang, N Wang, YH Guan, X Chen… - Nanoscale, 2023 - pubs.rsc.org
Cancer immunotherapy, which harnesses the immune system to fight cancer, has begun to
make a breakthrough in clinical applications. Dendritic cells (DCs) are the bridge linking …

Development of functionalized nanoparticles for vaccine delivery to dendritic cells: a mechanistic approach

JM Silva, G Vandermeulen, VG Oliveira, SN Pinto… - …, 2014 - Taylor & Francis
Aim: Produce biodegradable nanoparticles to target antigen-presenting cells (APCs) and
evaluate their potential to be used as a vaccine delivery system. Materials & methods …

Modulation of dendritic cells by nanotechnology-based immunotherapeutic strategies

J Mograo, CA da Costa, R Gaspar… - Journal of biomedical …, 2016 - ingentaconnect.com
In preceding decades, different mechanisms have been proposed to “instruct” dendritic cells
(DCs) to induce immune responses against tumor antigens (TAs), thus breaking immune …