Diabetic cardiomyopathy (DCM) is the leading cause of death worldwide, and oxidative
stress was discovered to serve an important role in the pathophysiology of the condition. An …

Diabetic cardiomyopathy (DCM), as one of the major cardiac complications in diabetic
patients, is known to related with oxidative stress that is due to a severe imbalance between …

Exposure to high levels of glucose induces the production of reactive oxygen species (ROS)
in cardiomyocytes that may contribute to the development of cardiomyopathy in diabetes …

Diabetes is a chronic disease that induces many comorbidities, including cardiovascular
disease, nephropathy, and liver damage. Many mechanisms have been suggested as to …

High glucose-induced oxidative stress is a major contributing mechanism to the
development of diabetic cardiomyopathy. Nrf2 is an emerging critical regulator of cellular …

OBJECTIVE Oxidative stress is implicated in cardiac insulin resistance, a critical risk factor
for cardiac failure, but the direct evidence remains missing. This study explored a causal link …

Hyperglycemia leads to excess reactive oxygen species (ROS) generation, which causes
many diabetic complications, such as cardiomyopathy. Nuclear factor erythroid 2‐related …

Macrovascular complications develop in over a half of the diabetic individuals, resulting in
high morbidity and mortality. This poses a severe threat to public health and a heavy burden …

Diabetic cardiomyopathy is one of the main causes of heart failure and death in patients with
diabetes mellitus. Reactive oxygen species produced excessively in diabetes mellitus cause …

Diabetic cardiomyopathy and nephropathy are two major causes of death of patients with
diabetes. Extra generation of reactive oxygen species (ROS), induced by hyperglycemia, is …