Evolution of anaesthesia has been largely helped by progress of evidence-based medicine.
In spite of many advancements in anaesthesia techniques and availability of newer and …

Skilled management of sick premature babies and very young children has resulted in
numerous exposures of their brains to a variety of anesthetic agents designed to achieve the …

Introduction: There is data amassing in the literature regarding the potentially adverse
effects of anaesthesia exposure on the developing human brain. The purpose of this article …

Despite the long history of paediatric anaesthesia, there is still much to be discovered
regarding how exposure to anaesthesia affects the developing brain. Given that commonly …

RISK FACTORS Millions of children undergo anesthesia annually and many of them are
younger than 3 years old. Clinicians and parents frequently ask the question: is anesthesia …

During the past two decades, a vast number of studies done on rodents and nonhuman
primates have implicated general anesthetic exposure of developing brains in producing …

Pre-clinical experimental evidence, along with a plausible biological rational suggests that
exposure of neonates and young children to anesthesia may harm brain development …

Abstract In 2017, the Food and Drug Administration published a safety recommendation to
limit the exposure to general anesthesia as much as possible below the age of three …

Anesthesia kills neurons in the brain of infantile animals, including primates, and causes
permanent and progressive neurocognitive decline. The anesthesia community and …

As the recent update of General Anaesthesia compared to Spinal anaesthesia (GAS) studies
has been published in 2019, together with other clinical evidence, the human studies …