The complexity of the phosphatase, PP2A, is being unravelled and current research is
increasingly providing information on the association of deregulated PP2A function with …

It should be noted that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is a protein
encoded by the PDPK1 gene, which plays a key role in the signaling pathways activated by …

Protein phosphatase 4 regulatory subunit 1 (PP4R1) has been shown to play a role in the
regulation of centrosome maturation, apoptosis, DNA repair, and tumor necrosis factor …

Gastric cancer (GC) is one of the most common cancers and the second leading cause of
cancer deaths in the world. Many factors have been reported regarding the progression and …

Cancer metastasis is a complex mechanism involving multiple processes. Previously, our
integrative proteome, transcriptome, and phosphoproteome study reported that the levels of …

PyK2 is a member of the proline-rich tyrosine kinase and focal adhesion kinase families and
is ubiquitously expressed. PyK2 is mainly activated by stimuli, such as activated Src kinases …

Background The serine/threonine kinase PAK1 is an important regulator of cell motility. Both
PAK1 and the hormone/cytokine prolactin (PRL) have been implicated in breast cancer cell …

In this study, we aimed to investigate the antitumor effect of LYG-202, a newly synthesized
piperazine-substituted derivative of flavonoid on human breast cancer cells and illustrate the …

Abstract Glutamate Ionotropic Receptor Kainate Type Subunit 3 (GRIK3) is an important
excitatory neurotransmitter receptor that plays a significant role in various …

Aim To explore the effects of protein phosphatase 2 regulatory subunit B''Alpha (PPP2R3A)
on the proliferation and migration of liver cancer cells. Methods Expression of PPP2R3A in …