Human telomerase reverse transcriptase gene promoter mutation in serum of patients with hepatocellular carcinoma
S Ako, K Nouso, H Kinugasa, H Matsushita… - Oncology, 2020 - karger.com
Background: Mutations in the human telomerase reverse transcriptase (hTERT) gene
promoter have been reported in hepatocellular carcinoma (HCC); however, analyses of …
promoter have been reported in hepatocellular carcinoma (HCC); however, analyses of …
[PDF][PDF] Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factors
J Jiao, GP Watt, HL Stevenson… - Hepatology …, 2018 - Wiley Online Library
Telomerase reverse transcriptase (TERT) mutation is the most frequent genetic alteration in
hepatocellular carcinoma (HCC). Our aims were to investigate whether TERT mutations can …
hepatocellular carcinoma (HCC). Our aims were to investigate whether TERT mutations can …
[HTML][HTML] Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations
AIM: To determine the mutation status of human telomerase reverse transcriptase gene
(TERT) promoter region in hepatocellular carcinoma (HCC) from different geographical …
(TERT) promoter region in hepatocellular carcinoma (HCC) from different geographical …
Clinical significance of telomerase reverse-transcriptase promoter mutations in hepatocellular carcinoma
Simple Summary Activating mutations in the promoter region of TERT (TERTp) gene are
frequently observed in low-and high-grade dysplastic nodules and defined as early events …
frequently observed in low-and high-grade dysplastic nodules and defined as early events …
Prediction of the prognosis of advanced hepatocellular carcinoma by TERT promoter mutations in circulating tumor DNA
M Hirai, H Kinugasa, K Nouso… - Journal of …, 2021 - Wiley Online Library
Background andAim Human telomerase reverse transcriptase (TERT) promoter mutations
were the most prevalent mutations in patients with hepatocellular carcinoma (HCC). We tried …
were the most prevalent mutations in patients with hepatocellular carcinoma (HCC). We tried …
Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma
Y Takuma, K Nouso, Y Kobayashi… - Journal of …, 2004 - Wiley Online Library
Abstract Background and Aim: Telomerase activation is essential for the immortality of
cancer cells. The expression of telomerase reverse transcriptase (hTERT), the catalytic …
cancer cells. The expression of telomerase reverse transcriptase (hTERT), the catalytic …
Clinicopathological characteristics of TERT promoter mutation and telomere length in hepatocellular carcinoma
Promoter mutations in telomerase reverse transcriptase (TERT) and telomere length have
been studied in various tumors. In the present study, the frequency and clinical …
been studied in various tumors. In the present study, the frequency and clinical …
[HTML][HTML] TERT promoter mutation in resectable hepatocellular carcinomas: a strong association with hepatitis C infection and absence of hepatitis B infection
YL Chen, YM Jeng, CN Chang, HJ Lee, HC Hsu… - International Journal of …, 2014 - Elsevier
Introduction Mutation in the core promoter of the telomerase reverse transcriptase (TERT)
gene was determined to be a frequent event in malignant melanoma and other cancers …
gene was determined to be a frequent event in malignant melanoma and other cancers …
[HTML][HTML] Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma
W Huang, W Zhou, C Li, Y Yang, YK Shang, C Chen… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Reactivation of telomerase is a critical step in the development of hepatocellular carcinoma
(HCC). Here we identified the frequency of mutations in telomerase reverse transcriptase …
(HCC). Here we identified the frequency of mutations in telomerase reverse transcriptase …
Detection of TERT promoter mutation in serum cell‐free DNA using wild‐type blocking PCR combined with Sanger sequencing in hepatocellular carcinoma
N Akuta, F Suzuki, M Kobayashi… - Journal of Medical …, 2020 - Wiley Online Library
Telomerase reverse transcriptase (TERT) promoter mutation is the most frequent genetic
alteration in hepatocellular carcinoma (HCC). However, there is currently no suitable highly …
alteration in hepatocellular carcinoma (HCC). However, there is currently no suitable highly …