Capsule expression in Streptococcus mitis modulates interaction with oral keratinocytes and alters susceptibility to human antimicrobial peptides

HV Rukke, SA Engen, K Schenck… - Molecular oral …, 2016 - Wiley Online Library
Streptococcus mitis is a colonizer of the oral cavity and the nasopharynx, and is closely
related to Streptococcus pneumoniae. Both species occur in encapsulated and …

Identification of a functional capsule locus in Streptococcus mitis

HV Rukke, IK Hegna… - Molecular oral …, 2012 - Wiley Online Library
The polysaccharide capsule of Streptococcus pneumoniae is a hallmark for virulence in
humans. In its close relative Streptococcus mitis, a common human commensal, analysis of …

Protective role of the capsule and impact of serotype 4 switching on Streptococcus mitis

HV Rukke, RS Kalluru, U Repnik, A Gerlini… - Infection and …, 2014 - Am Soc Microbiol
The polysaccharide capsule surrounding Streptococcus pneumoniae is essential for
virulence. Recently, Streptococcus mitis, a human commensal and a close relative of S …

Streptococcus mitis: walking the line between commensalism and pathogenesis

J Mitchell - Molecular oral microbiology, 2011 - Wiley Online Library
Streptococcus mitis is a viridans streptococcus and a normal commensal of the human
oropharynx. However, S. mitis can escape from this niche and cause a variety of infectious …

Capsular Polysaccharide Expression in Commensal Streptococcus Species: Genetic and Antigenic Similarities to Streptococcus pneumoniae

UB Skov Sørensen, K Yao, Y Yang, H Tettelin, M Kilian - MBio, 2016 - Am Soc Microbiol
Expression of a capsular polysaccharide is considered a hallmark of most invasive species
of bacteria, including Streptococcus pneumoniae, in which the capsule is among the …

[HTML][HTML] Streptococcus mitis Expressing Pneumococcal Serotype 1 Capsule

FC Lessa, J Milucky, NG Rouphael, NM Bennett… - Scientific reports, 2018 - nature.com
Streptococcus pneumoniae's polysaccharide capsule is an important virulence factor;
vaccine-induced immunity to specific capsular polysaccharide effectively prevents disease …

The core promoter of the capsule operon of Streptococcus pneumoniae is necessary for colonization and invasive disease

MG Shainheit, M Mulé, A Camilli - Infection and immunity, 2014 - Am Soc Microbiol
Streptococcus pneumoniae is a commensal of the human nasopharynx but can cause
invasive diseases, including otitis media, pneumonia, sepsis, and meningitis. The capsular …

Characterization of a signaling system in Streptococcus mitis that mediates interspecies communication with Streptococcus pneumoniae

R Junges, K Sturød, G Salvadori… - Applied and …, 2019 - Am Soc Microbiol
Streptococcus mitis is found in the oral cavity and nasopharynx and forms a significant
portion of the human microbiome. In this study, in silico analyses indicated the presence of …

[HTML][HTML] Effects of Expression of Streptococcus pneumoniae PspC on the Ability of Streptococcus mitis to Evade Complement-Mediated Immunity

H Marshall, RJ José, M Kilian, FC Petersen… - Frontiers in …, 2021 - frontiersin.org
Streptococcus pneumoniae and Streptococcus mitis are genetically closely related and both
frequently colonise the naso-oropharynx, yet S. pneumoniae is a common cause of invasive …

Analysis of the Polysaccharide Capsule of the Systemic Pathogen Streptococcus iniae and Its Implications in Virulence

BA Lowe, JD Miller, MN Neely - Infection and immunity, 2007 - Am Soc Microbiol
Systemic pathogens have developed numerous strategies for evading the defenses of the
host, permitting dissemination and multiplication in various tissues. One means of survival in …