Asf1 is a highly conserved histone chaperone that regulates tightly coupled nucleosome
assembly/disassembly process. We observed that Plasmodium falciparum Asf1 (PfAsf1) is …

Nucleosome assembly in P. áfalciparum could be the key process in maintaining its
genomic integrity as DNA replicates more than once per cell cycle during several stages of …

The anti-silencing function protein 1 (Asf1) is a chaperone that forms a complex with
histones H3 and H4 facilitating dimer deposition and removal from chromatin. Most …

Abstract Background Nucleosome assembly proteins (NAPs) are histone chaperones that
are crucial for the shuttling and incorporation of histones into nucleosomes. NAPs participate …

The packaging of the eukaryotic genome into chromatin is likely to be mediated by
chromatin assembly factors, including histone chaperones. We investigated the function of …

Abstract RbAp46/RBBP7 and RbAp48/RBBP4 are WD40-repeat histone chaperones and
chromatin adaptors that reside in multiple complexes involved in maintenance of chromatin …

Background: Asf1 is a ubiquitous eukaryotic histone binding and deposition protein that
mediates nucleosome formation in vitro and is required for genome stability in vivo. Studies …

Histone chaperones have been implicated in nucleosome assembly and disassembly as
well as histone modification. ASF1 is a highly conserved histone H3/H4 chaperone that …

In this issue of Cell, English et al.(2006) present the first crystal structure of a histone
chaperone (Asf1) bound to histones (the H3/H4 heterodimer). The structure provides …

Abstract Human HIRA, ASF1a, ASF1b and CAF-1 are evolutionally conserved histone
chaperones that form multiple functionally distinct chromatin-assembly complexes, with roles …