Choreito, a Kampo medicine attenuates detrusor overactivity and bladder pain symptoms in rat tranilast‐induced interstitial cystitis/bladder pain syndrome‐like model
Y Tokita, K Sugaya, S Nishijima… - Neurourology and …, 2023 - Wiley Online Library
Aims Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic inflammatory condition
of the bladder. However, there are only a few medicines that are of pharmaceutical grade …
of the bladder. However, there are only a few medicines that are of pharmaceutical grade …
Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn …
The role of anandamide in the development of inflammatory hyperalgesia and visceral
hyperreflexia was studied in the rat urinary bladder. Animals were given intraperitoneal …
hyperreflexia was studied in the rat urinary bladder. Animals were given intraperitoneal …
Characterization and validation of a chronic model of cyclophosphamide-induced interstitial cystitis/bladder pain syndrome in rats
C Augé, X Gamé, N Vergnolle, P Lluel… - Frontiers in …, 2020 - frontiersin.org
Interstitial cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic inflammatory disease
characterized by visceral pain and voiding symptoms. IC/BPS is still an unsolved enigma …
characterized by visceral pain and voiding symptoms. IC/BPS is still an unsolved enigma …
A model in female rats with phenotypic features similar to interstitial cystitis/bladder pain syndrome
This report describes methodological and exploratory investigations of the zymosan-induced
neonatal bladder inflammation (NBI) model of interstitial cystitis/bladder pain syndrome …
neonatal bladder inflammation (NBI) model of interstitial cystitis/bladder pain syndrome …
Deletion or pharmacological blockade of TLR4 confers protection against cyclophosphamide-induced mouse cystitis
MG de Oliveira, FZ Mónica… - American Journal …, 2018 - journals.physiology.org
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic inflammatory disease
without consistently effective treatment. We investigate the role of toll-like receptor 4 (TLR4) …
without consistently effective treatment. We investigate the role of toll-like receptor 4 (TLR4) …
Ca2+/calmodulin-dependent protein kinase II is associated with pelvic pain of neurogenic cystitis
W Yang, CN Rudick, E Hoxha… - American Journal …, 2012 - journals.physiology.org
Interstitial cystitis/painful bladder syndrome is a chronic bladder inflammatory disease of
unknown etiology that is often regarded as a neurogenic cystitis. Interstitial cystitis is …
unknown etiology that is often regarded as a neurogenic cystitis. Interstitial cystitis is …
Detrusor overactivity induced by intravesical application of adenosine 5′-triphosphate under different delivery conditions in rats
J Nishiguchi, Y Hayashi, MB Chancellor, F de Miguel… - Urology, 2005 - Elsevier
OBJECTIVES: To investigate the effects of intravesical application of adenosine 5′-
triphosphate (ATP) on bladder activity to elucidate the role of urothelial barrier function and …
triphosphate (ATP) on bladder activity to elucidate the role of urothelial barrier function and …
Modulation of bladder function by luminal adenosine turnover and A1 receptor activation
HS Prakasam, H Herrington… - American Journal …, 2012 - journals.physiology.org
The bladder uroepithelium transmits information to the underlying nervous and musculature
systems, is under constant cyclical strain, expresses all four adenosine receptors (A1, A2A …
systems, is under constant cyclical strain, expresses all four adenosine receptors (A1, A2A …
Ceftriaxone inhibits stress‐induced bladder hyperalgesia and alters cerebral micturition and nociceptive circuits in the rat: A multidisciplinary approach to the study of …
DP Holschneider, Z Wang, H Chang… - Neurourology and …, 2020 - Wiley Online Library
Aims Emotional stress plays a role in the exacerbation and development of interstitial
cystitis/bladder pain syndrome (IC/BPS). Given the significant overlap of brain circuits …
cystitis/bladder pain syndrome (IC/BPS). Given the significant overlap of brain circuits …
Pathophysiological role of transient receptor potential ankyrin 1 in a mouse long-lasting cystitis model induced by an intravesical injection of hydrogen peroxide
S Oyama, K Dogishi, M Kodera, M Kakae… - Frontiers in …, 2017 - frontiersin.org
Chronic inflammatory bladder disorders, such as interstitial cystitis/bladder pain syndrome,
are associated with poor quality of life. The exact pathological processes remain unclear, but …
are associated with poor quality of life. The exact pathological processes remain unclear, but …