The effect of HTLV-1 virulence factors (HBZ, Tax, proviral load), HLA class I and plasma neopterin on manifestation of HTLV-1 associated myelopathy tropical spastic …

H Tarokhian, M Taghadosi, H Rafatpanah, T Rajaei… - Virus research, 2017 - Elsevier
Background Previous studies have suggested debatable roles of Tax and HBZ gene
expression in the pathogenesis of HTLV-1-associated myelopathy/tropical spastic …

In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical …

M Saito, T Matsuzaki, Y Satou, J Yasunaga, K Saito… - Retrovirology, 2009 - Springer
Background Recently, human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper
factor (HBZ), encoded from a minus strand mRNA was discovered and was suggested to …

Clinical subtype of HAM/TSP based on clinical course and laboratory findings

Y Yamano, T Sato, N Araya, N Yagishita, Y Shimizu… - Retrovirology, 2011 - Springer
The clinical course and disease activity of patients with HTLV-1 associated
myelopathy/tropical spastic paraparesis (HAM/TSP) are different among patients. Therefore …

Familial clusters of HTLV-1-associated myelopathy/tropical spastic paraparesis

S Nozuma, E Matsuura, T Matsuzaki, O Watanabe… - PLoS …, 2014 - journals.plos.org
Objective HTLV-1 proviral loads (PVLs) and some genetic factors are reported to be
associated with the development of HTLV-1-associated myelopathy/tropical spastic …

[HTML][HTML] HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): A comparative study to identify factors that influence disease progression

E Matsuura, S Nozuma, Y Tashiro, R Kubota… - Journal of the …, 2016 - Elsevier
Abstract Objective HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
can progress slowly or rapidly even though a set of symptoms such as spastic paraparesis …

Proviral load and the balance of serum cytocines in HTLV-1-asymptomatic infection and in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

ALB Starling, OA Martins-Filho, JR Lambertucci… - Acta tropica, 2013 - Elsevier
This study compared the proviral load and the plasma cytokine profiles (interleukin-IL-2, IL-
4, IL-6, IL-10, TNF-α, IFN-γ) in 87 HTLV-1-infected individuals, including 28 with HTLV-1 …

An insight to HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis; evidence from high-throughput data integration and meta-analysis

SH Mozhgani, M Piran, M Zarei-Ghobadi, M Jafari… - Retrovirology, 2019 - Springer
Background Human T-lymphotropic virus 1-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a progressive disease of the central nervous system that …

Evaluation of host genetic and viral factors as surrogate markers for HTLV‐1‐associated myelopathy/tropical spastic paraparesis in Peruvian HTLV‐1‐infected …

M Talledo, G Lopez, JR Huyghe… - Journal of medical …, 2010 - Wiley Online Library
Human T‐lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a complication that affects up to 5% of HTLV‐1‐infected …

High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic virus type 1-infected clones are associated with human T-cell …

OM Espíndola, LC Oliveira, P Ferreira, ACCB Leite… - Intervirology, 2015 - karger.com
Background/Aims: Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that
causes a persistent infection, and only 0.5-5% of infected individuals will develop HTLV-1 …

HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) inflammatory network

DU Goncalves, FA Proietti… - … & Allergy-Drug …, 2008 - ingentaconnect.com
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a systemic
immune-mediated inflammatory disease and tissues other than nervous can be damaged …