Ischemia has been a persistent and largely unavoidable element in solid organ
transplantation, contributing to graft deterioration and adverse post-transplant outcomes. In …

Background Organs from donation after circulatory death (DCD) are increasingly used for
liver transplantation, due to the persisting organ shortage and waiting list mortality. However …

Avoidance of cold ischaemic preservation damage and repair of injury sustained during
warm ischaemia and organ procurement would potentially allow many livers from extended …

The success of liver transplantation has resulted in a dramatic organ shortage. In most
transplant regions 20-30% of patients on the waiting list for liver transplantation die without …

The need for donor pool expansion in liver transplantation has increased utilization of grafts
from so-called extended-criteria donors. Machine perfusion technology can improve …

Despite increasing donor numbers, waiting lists and pre‐transplant mortality continue to
grow in many countries. The number of donor organs suitable for liver transplantation is …

Donor organ shortage necessitates use of less than optimal donor allografts for
transplantation. The current cold storage preservation technique fails to preserve marginal …

Dynamic preservation strategies such as hypothermic machine perfusion are increasingly
discussed to improve liver graft quality before transplantation. This review summarizes …

Warm ex-vivo liver perfusion has established itself as a novel approach for the preservation
of liver grafts for transplantation. Although the optimal perfusion conditions and techniques …

Does Ischemia Free Liver Procurement Under Normothermic Perfusion Benefit the Outcome of
Liver Transplantation? - PMC Back to Top Skip to main content NIH NLM Logo Access keys …