Comprehensive analysis of epigenetic modifications and immune-cell infiltration in tissues from patients with systemic lupus erythematosus
Z He, S Zhou, M Yang, Z Zhao, Y Mei, Y Xin, M Zhao… - …, 2022 - Taylor & Francis
Aim: To explore potential abnormal epigenetic modifications and immune-cell infiltration in
tissues from systemic lupus erythematosus (SLE) patients. Materials & methods: To utilize …
tissues from systemic lupus erythematosus (SLE) patients. Materials & methods: To utilize …
[HTML][HTML] Identification of key biomarkers and immune infiltration in systemic lupus erythematosus by integrated bioinformatics analysis
X Zhao, L Zhang, J Wang, M Zhang, Z Song… - Journal of Translational …, 2021 - Springer
Background Systemic lupus erythematosus (SLE) is a multisystemic, chronic inflammatory
disease characterized by destructive systemic organ involvement, which could cause the …
disease characterized by destructive systemic organ involvement, which could cause the …
[HTML][HTML] Identifying key genes in CD4+ T cells of systemic lupus erythematosus by integrated bioinformatics analysis
Z Li, Z Wang, T Sun, S Liu, S Ding, L Sun - Frontiers in Genetics, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by
excessive activation of T and B lymphocytes and breakdown of immune tolerance to …
excessive activation of T and B lymphocytes and breakdown of immune tolerance to …
Immune cell multiomics analysis reveals contribution of oxidative phosphorylation to B-cell functions and organ damage of lupus
Y Takeshima, Y Iwasaki, M Nakano… - Annals of the …, 2022 - ard.bmj.com
Objective Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune
disease. While the long-term prognosis has greatly improved, better long-term survival is still …
disease. While the long-term prognosis has greatly improved, better long-term survival is still …
Microarray to deep sequencing: transcriptome and miRNA profiling to elucidate molecular pathways in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical
manifestations and autoantibody repertoires. The etiology of SLE is multifactorial involving …
manifestations and autoantibody repertoires. The etiology of SLE is multifactorial involving …
[HTML][HTML] Identification of diagnostic biomarkers in systemic lupus erythematosus based on bioinformatics analysis and machine learning
Z Jiang, M Shao, X Dai, Z Pan, D Liu - Frontiers in genetics, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that affects several
organs and causes variable clinical symptoms. Exploring new insights on genetic factors …
organs and causes variable clinical symptoms. Exploring new insights on genetic factors …
[HTML][HTML] Bioinformatics analysis of differentially expressed gene profiles associated with systemic lupus erythematosus
C Wu, Y Zhao, Y Lin, X Yang… - Molecular …, 2018 - spandidos-publications.com
DNA microarray and high-throughput sequencing have been widely used to identify the
differentially expressed genes (DEGs) in systemic lupus erythematosus (SLE). However, the …
differentially expressed genes (DEGs) in systemic lupus erythematosus (SLE). However, the …
[HTML][HTML] Exploring the shared molecular mechanisms between systemic lupus erythematosus and primary Sjögren's syndrome based on integrated bioinformatics and …
Y Cui, H Zhang, Z Wang, B Gong, H Al-Ward… - Frontiers in …, 2023 - frontiersin.org
Background Systemic lupus erythematosus (SLE) and primary Sjögren's syndrome (pSS)
are common systemic autoimmune diseases that share a wide range of clinical …
are common systemic autoimmune diseases that share a wide range of clinical …
[HTML][HTML] Identification of key interferon-stimulated genes for indicating the condition of patients with systemic lupus erythematosus
M Shen, C Duan, C Xie, H Wang, Z Li, B Li… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with highly
heterogeneous clinical symptoms and severity. There is complex pathogenesis of SLE, one …
heterogeneous clinical symptoms and severity. There is complex pathogenesis of SLE, one …
Investigation of systemic lupus erythematosus (SLE) with integrating transcriptomics and genome wide association information
AE Gorji, Z Roudbari, A Alizadeh, B Sadeghi - Gene, 2019 - Elsevier
Systemic lupus erythematous (SEL) is a heterogeneous, systemic autoimmune disorder
which is defined by its autoantibody pattern. Transcriptomic data analysis has shown …
which is defined by its autoantibody pattern. Transcriptomic data analysis has shown …