The janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling
pathway is associated with the regulation of essential cellular mechanisms, such as …

Human papillomaviruses (HPVs) are small, DNA viruses that cause around 5% of all
cancers in humans, including almost all cervical cancer cases and a significant proportion of …

Persistent infection with high-risk human papillomavirus (HPV) is the underlying cause of~
5% of all human cancers, including the majority of cervical carcinomas and many other ano …

Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription
factor constitutively active and aberrantly expressed in cervical cancer. However, the …

Persistent human papillomavirus (HPV) infection is the leading cause of cervical cancer.
Although the fundamental link between HPV infection and oncogenesis is established, the …

Background: Stat3 is a member of the Janus-activated kinase/STAT signalling pathway. It
normally resides in the cytoplasm and can be activated through phosphorylation. Activated …

JAK-STAT signalling is a cornerstone to cancer progression, either as a tumour intrinsic
driver of cancer growth/metastasis, or as a modulator of immune surveillance. This Special …

Recent highlights in understanding molecular nature of signaling pathways that mediate
biological effects of various external stimuli and control number of normal physiological …

Ovarian carcinoma is the fifth leading cause of death among women in the United States.
Persistent activation of STAT3 is frequently detected in ovarian carcinoma. STAT3 is …

Background Recent observations indicate potential role of transcription factor STAT3 in
cervical cancer development but its role specifically with respect to HPV infection is not …