[HTML][HTML] Role of interleukin-12 family cytokines in the cellular response to mycobacterial disease

P Méndez-Samperio - International Journal of Infectious Diseases, 2010 - Elsevier
Interleukin (IL)-12 is a multifunctional cytokine acting as a key regulator of cell-mediated
immune responses through the differentiation of naïve CD4+ T cells into type 1 helper T cells …

IL-17 in protective immunity to intracellular pathogens

SA Khader, R Gopal - Virulence, 2010 - Taylor & Francis
The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in
protective immunity against extracellular bacterial infections is well established. In contrast …

Regulation of interleukin-12 by interleukin-10, transforming growth factor-β, tumor necrosis factor-α, and interferon-γ in human monocytes infected with Mycobacterium …

SA Fulton, JV Cross, ZT Toossi… - The Journal of infectious …, 1998 - academic.oup.com
Abstract Regulation of interleukin (IL)-12 production by coexpression of tumor necrosis
factor (TNF)-α, IL-10, and transforming growth factor (TGF)-β in human monocytes infected …

Interleukin-12 gene expression in human monocyte-derived macrophages stimulated with Mycobacterium bovis BCG: cytokine regulation and effect of NK cells

H Matsumoto, K Suzuki, K Tsuyuguchi… - Infection and …, 1997 - Am Soc Microbiol
Macrophage-derived interleukin-12 (IL-12) is essential for the activation of a protective
immune response against intracellular pathogens. In this study, we examined the regulation …

Recent insights into microbial triggers of interleukin-10 production in the host and the impact on infectious disease pathogenesis

BL Duell, CK Tan, AJ Carey, F Wu… - FEMS Immunology & …, 2012 - academic.oup.com
Since its initial description as a Th2-cytokine antagonistic to interferon-alpha and
granulocyte-macrophage colony-stimulating factor, many studies have shown various anti …

[HTML][HTML] IL-26 contributes to host defense against intracellular bacteria

AT Dang, RMB Teles, DI Weiss… - The Journal of …, 2019 - Am Soc Clin Investig
IL-26 is an antimicrobial protein secreted by Th17 cells that has the ability to directly kill
extracellular bacteria. To ascertain whether IL-26 contributes to host defense against …

Endogenous interleukin-12 is involved in resistance of mice to Mycobacterium avium complex infection

BM Saunders, Y Zhan, C Cheers - Infection and immunity, 1995 - Am Soc Microbiol
Acquired cellular resistance against Mycobacterium avium complex (MAC) infections
involves the induction of Th1 type gamma interferon (IFN-gamma)-producing T cells …

IL-12 family cytokines: general characteristics, pathogenic microorganisms, receptors, and signalling pathways

P Behzadi, E Behzadi, R Ranjbar - Acta microbiologica et …, 2016 - akjournals.com
Among a wide range of cytokines, the Interleukin 12 (IL-12) family has its unique structural,
functional, and immunological characteristics that have made this family as important …

Regulation of Interleukin-8 by Interleukin-10 and Transforming Growth Factor β in Human Monocytes Infected with Mycobacterium bovis

P Méndez-Samperio, E García… - Clinical and Vaccine …, 2002 - Am Soc Microbiol
Recent studies indicate that interleukin 8 (IL-8) production contributes to the host immune
responses against mycobacterial infection. In this study, we were interested to determine …

Interleukin‐17 as an effector molecule of innate and acquired immunity against infections

G Matsuzaki, M Umemura - Microbiology and immunology, 2007 - Wiley Online Library
Abstract Interleukin (IL)‐17 is a proinflammatory cytokine which induces differentiation and
migration of neutrophils through induction of cytokines and chemokines including …